17650-84-9
17650-84-9 結(jié)構(gòu)式
基本信息
莰非醇-3-O-蕓香糖苷
莰菲醇-3-O-蕓香糖苷
山柰酚-3-O-蕓香糖苷
山柰酚-3-O-蕓香糖苷(標(biāo)準(zhǔn)品)
山柰酚-3-O-蕓香糖苷(煙花苷)
山柰酚-3-O-蕓香糖苷, 來源于紅花
莰菲醇-3-O-蕓香糖苷, ≥98.0%(HPLC)
山奈酚-3-O-蕓香糖苷,又名 莰菲醇-3-O-蕓香糖苷
煙花苷,莰菲醇-3-O-蕓香糖苷,莰非醇-3-O-蕓香糖苷
NICOTIFLORIN
Nicotoflorin
Nicotifiorin
Nicotiflorine
Nicotifloroside
Nictoflorin (incorr
Rutoside EP Impurity B
KAEMPFEROL-3-RUTINOSIDE
Aempferol-3-O-rutinoside
物理化學(xué)性質(zhì)
安全數(shù)據(jù)
應(yīng)用領(lǐng)域
藥理藥效:降血脂、善癡呆癥狀和記憶保護(hù)
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/11/08 | HY-N1475 | 莰菲醇-3-O-蕓香糖苷 Nicotiflorin | 17650-84-9 | 5mg | 2200元 |
| 2024/11/08 | HY-N1475 | 莰菲醇-3-O-蕓香糖苷 Nicotiflorin | 17650-84-9 | 10mM * 1mLin DMSO | 2420元 |
| 2024/11/08 | S3267 | 莰菲醇-3-O-蕓香糖苷 Kaempferol-3-O-rutinoside | 17650-84-9 | 1mg | 1170.54元 |
常見問題列表
| Target | Value |
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p-JAK2
() | |
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p-STAT3
() | |
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caspase-3
() | |
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Bax
() | |
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Bcl-2
() |
For primarily cultured neurons suffered 2 h hypoxia followed by 24 h reoxygenation, nicotiflorin significantly attenuates cell death and reduces LDH release. Morphological observation also directly confirms its protective effect on neuron. After total 4 h hypoxia and 12 h reoxygenation, eNOS activity, mRNA and protein levels in the primarily cultured rat cerebral blood vessel endothelial cells treated with nicotiflorin (25-100 g/mL) 2 h after onset of hypoxia are significantly higher than eNOS activity, mRNA and protein levels in the pure H-R cells and also higher than eNOS activity, mRNA and protein levels in cells cultured under normoxic conditions.
At doses of 2.5, 5 and 10 mg/kg, nicotiflorin administered immediately after the onset of ischemia markedly reduces brain infarct volume and neurological deficits. Nicotiflorin (2.5-10 mg/kg) administered after onset of ischemia markedly reduces brain infarct volume by 24.5-63.2% and neurological deficits.