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1354945-69-9

中文名稱 替格瑞洛中間體1脫保護(hù)雜質(zhì)
英文名稱 2-[[(3aR,4S,6R,6aS)-6-(7-azanyl-5-propylsulfanyl-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyl-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy]ethanol
CAS 1354945-69-9
分子式 C17H26N6O4S
分子量 410.491
MOL 文件 1354945-69-9.mol
更新日期 2024/11/05 14:07:32
1354945-69-9 結(jié)構(gòu)式 1354945-69-9 結(jié)構(gòu)式

基本信息

中文別名
替卡格雷雜質(zhì)7
替格瑞洛雜質(zhì)59
替格格雷雜質(zhì)32
替格瑞洛相關(guān)化合物59
替格瑞洛中間體1脫保護(hù)雜質(zhì)
替格瑞洛雜質(zhì)8:中1脫保護(hù)
替格瑞洛雜質(zhì)E:氯代合環(huán)雜質(zhì)
(1S,2S,3R,5S)-3-(7-氯-5-(丙硫基)-3H-[1,2,3]三唑并[4,5-D]嘧啶-3-基)-5-(2-羥基乙氧基)環(huán)戊烷-1,2-二醇
(1S,2S,3R,5S)-3-[7-氯-5-(丙基硫基)-3H-[1,2,3]三唑并[4,5-D]嘧啶-3-基]-5-(2-羥基乙氧基)環(huán)戊烷-1,2-二醇
英文別名
Ticagrelor Related Compound 59
Ticagrelor Impurity E: Chlorocyclic Impurity
(1S,2S,3R,5S)-3-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)
2-[[(3aR,4S,6R,6aS)-6-(7-azanyl-5-propylsulfanyl-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyl-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy]ethanol
所屬類別
分析化學(xué):藥典標(biāo)準(zhǔn)品和雜質(zhì)標(biāo)準(zhǔn)品

應(yīng)用領(lǐng)域

用途一
(1S,2S,3R,5S)-3-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol is an intermediate in the synthesis of metaboltes of Ticagrelor (T437700) which is the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel.
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