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115532-50-8

中文名稱 四甲基若丹明甲酯酸銨
英文名稱 TETRAMETHYLRHODAMINE METHYL ESTER PERCHLORATE
CAS 115532-50-8
分子式 C25H25ClN2O7
分子量 500.93
MOL 文件 115532-50-8.mol
更新日期 2024/11/26 11:42:17
115532-50-8 結構式 115532-50-8 結構式

基本信息

中文別名
四甲基羅丹明甲酯
羅丹明甲酯高氯酸鹽
四甲基若丹明甲酯酸銨
四甲基若丹明甲酯高氯酸鹽
四甲基羅丹明甲酯高氯酸鹽
TMRM[四甲基羅丹明甲酯]
英文別名
TMRM
T 668
TMRM, PERCHLORATE
Tetramethylrhodamin methylester perchlorate
TETRAMETHYLRHODAMINE METHYL ESTER PERCHLORATE
TMRM [TetraMethylrhodaMine, Methyl ester, perchlorate]
TMRM [Tetramethylrhodamine methyl ester] *CAS#: 115532-50-8*
3,6-bis(diMethylaMino)-9-(2-(Methoxycarbonyl)phenyl)xanthyliuM perchlorate
XanthyliuM, 3,6-bis(diMethylaMino)-9-[2-(Methoxycarbonyl)phenyl]-, perchlorate (1:1)
N-[6-(Dimethylamino)-9-[2-(methoxycarbonyl)phenyl]-3H-xanthen-3-ylidene]-N-methylmethanaminium Perchlorate
所屬類別
生物化工:熒光成像

物理化學性質

熔點274–276℃
儲存條件2-8°C
溶解度DMSO: soluble
形態(tài)crystals
顏色深綠色
最大波長(λmax)549 nm
BRN7162165
生物領域應用Detecting mitochondrial membrane potential; apoptosis assays; multidrug resistance assays

安全數據

危險性符號(GHS)GHS hazard pictograms
GHS07
警示詞警告
危險性描述H315-H335-H319
危險品標志Xi
危險類別碼36/37/38
安全說明26-36
WGK Germany3
海關編碼3204.20.8000
四甲基若丹明甲酯酸銨價格(試劑級)
報價日期產品編號產品名稱CAS號包裝價格
2024/11/0846456四甲基羅丹明甲酯高氯酸鹽
Tetramethylrhodamine methyl ester perchlorate
115532-50-825mg3577元
2024/11/08HY-D0984A四甲基若丹明甲酯酸銨
TMRM Perchlorate
115532-50-85mg500元
2024/11/08HY-D0984A四甲基若丹明甲酯酸銨
TMRM Perchlorate
115532-50-810mM * 1mLin DMSO551元

常見問題列表

生物活性
TMRM Perchlorate 是一種細胞滲透性陽離子親脂性紅色熒光染料 (λex=530 nm, λem=592 nm)。
體外研究

TMRM Perchlorate is a fluorescent probe (excitation, 530±21 nm; emission, 592±22 nm). The fluorescence signal in the presence of TMRM Perchlorate shows a slight decrease after the addition of glutamate, indicative of increased polarization of the mitochondrial inner membrane. In the presence of TMRM Perchlorate (2 μM) the coupled respiration with Complex I substrates or upon the addition of Complex II substrate is decreased by 27%. Exposure of hippocampal cultures to low concentrations of TMRM Perchlorate (50 to 500 nM) for 1 to 3 hours results in selective staining of mitochondria in both neurons and the underlying glial cells. Exposure of hippocampal cultures to high concentrations of TMRM Perchlorate (1 to 25 μM) stains mitochondria selectively and quickly, reaching a plateau after 5 to 10 min. Low concentrations of TMRM Perchlorate (50 to 200 nM) do not induce apoptosis, whereas higher concentrations (0.5 and 2.5 μM) enhance apoptosis (K D =?500 nM).

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