103898-11-9
中文名稱
N-叔丁氧羰基二乙胺
英文名稱
TERT-BUTYL N,N-BIS(2-HYDROXYETHYL)CARBAMATE
CAS
103898-11-9
分子式
C9H19NO4
分子量
205.25
MOL 文件
103898-11-9.mol
更新日期
2024/10/24 11:11:05
103898-11-9 結(jié)構(gòu)式
基本信息
中文別名
BOC-二乙醇胺N-叔丁氧羰基二乙胺
N-BOC-二乙醇胺
N-叔丁氧羰基二乙醇胺
N-叔丁氧羰基二乙胺 1G
二(2-羥乙基)氨基甲酸叔丁酯
N,N-雙(2-羥乙基)氨基甲酸叔丁酯
N-叔丁氧羰基二乙胺/N-BOC-二乙醇胺
英文別名
BOC-DIETHANOLAMINE1-Boc-diethanolamine
N-BOC-DIETHANOLAMINE
tert-Butyl bis(2-hydroxyethyl)
Boc-diethanolamine≥ 98% (Assay)
N-Boc-diethanolamine >=98.0% (GC)
tert-Butyl bis(2-hydroxyethyl)carbamate
Bis(2-hydroxyethyl)amine, N-BOC protected
TERT-BUTYL N,N-BIS(2-HYDROXYETHYL)CARBAMATE
Bis(2-hydroxyethyl)amine, N-BOC protected 97%
物理化學(xué)性質(zhì)
外觀性狀無色液體
沸點(diǎn)324.2±35.0 °C(Predicted)
密度1.085 g/mL at 20 °C(lit.)
折射率n20/D 1.461
儲(chǔ)存條件Inert atmosphere,2-8°C
酸度系數(shù)(pKa)14.29±0.10(Predicted)
形態(tài)液體或油
顏色無色
BRN4386562
CAS 數(shù)據(jù)庫103898-11-9
安全數(shù)據(jù)
常見問題列表
生物活性
N-Boc-diethanolamine 是一種 PROTAC 連接橋，屬于 Alkyl/ether 類。N-Boc-diethanolamine 可用于合成一系列 PROTAC 分子。N-Boc-diethanolamine 是一種可降解 (cleavable) 的 ADC 連接橋，用于抗體藥物結(jié)合物 (ADCs) 的合成。靶點(diǎn)
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Cleavable
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Alkyl/ether
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體外研究
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.