10030-78-1
10030-78-1 結(jié)構(gòu)式
基本信息
2-甲氨基-6-羥基嘌呤
6-羥基-2-氨甲基嘌呤
6-羥基-2-氨甲基嘌呤 10G
2-(甲基氨基)-1H-嘌呤-6(7H)-酮
2-(甲基氨基)-6,7-二氫-3H-嘌呤-6-酮
2-(MethylaMino)-7H-purin-6-ol
6-HYDROXY-2-METHYLAMINOPURINE
2-(MethylaMino)-1H-purin-6(7H)-one
2-methylamino-3,7-dihydropurin-6-one
1,7-Dihydro-2-(methylamino)-6H-purin-6-one
2-(methylamino)-6,7-dihydro-3H-purin-6-one
6H-Purin-6-one,1,9-dihydro-2-(methylamino)-
Endogenous Metabolite,Inhibitor,Bacterial,2 (Methylamino) 1H purin 6(7H) one,2(Methylamino)1Hpurin6(7H)one,inhibit,DNA/RNA Synthesis
物理化學(xué)性質(zhì)
常見問題列表
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Human Endogenous Metabolite
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2-(Methylamino)-1H-purin-6(7H)-one (N2-methylguanine) is found within both helical and looped regions of RNA secondary structure, and it can exist in either the s-cis or the s-trans rotamer. If there is a rotational preference for the methyl group, the effect of 2-(Methylamino)-1H-purin-6(7H)-one substitution may be specific to the sequence context depending upon which face of the base participates in hydrogen bonding. 2-(Methylamino)-1H-purin-6(7H)-one (N2-methylguanine) is the principal kinetic barrier for reverse transcription in the 1340 bases proximal to the 5' end of E. coli 16S rRNA. Transcription intermediates correspond to attenuation at the positions of 2-(Methylamino)-1H-purin-6(7H)-one in the rRNA sequence. The relaxation time for elongation of the cDNA through m2G is approximately 3 min.