| Identification | More | [Name]
Dimethylchloroacetal | [CAS]
97-97-2 | [Synonyms]
1,1-DIMETHOXY-2-CHLOROETHANE
1-CHLORO-2,2-DIMETHOXYETHANE
2-CHLORO-1,1-DIMETHOXYETHANE
2-CHLOROACETALDEHYDE DIMETHYL ACETAL
CADMA
CHLOROACETALDEHYDE DIMETHYL ACETAL
CHLORODIMETHYL ACETAL
DIMETHYL CHLOROACETAL
METHYL CHLOROACETAL
2-chloro-1,1-dimethoxy-ethan
Acetaldehyde, chloro-, dimethyl acetal
Dimethyl chloracetal
CHLOROACETALDEHYDE DIMETHYL ACETAL, WACK ER QUALITY
CHLOROACETALDEHYDE DIMETHYL ACETAL, STAB .
Chloroacetaldehydedimethylacetal,98%
Ethane, 2-chloro-1,1-dimethoxy-
2-Chlor-1,1-dimethoxyethan
CHLORACETALDEHYDDIMETHYLACETAL
2-Chloro-1,1-dimethoxyethane, CADMA, Dimethyl chloroacetal
2-Chloro-1,1-dimethoxyethane, Dimethyl chloroacetal | [EINECS(EC#)]
202-624-0 | [Molecular Formula]
C4H9ClO2 | [MDL Number]
MFCD00000948 | [Molecular Weight]
124.57 | [MOL File]
97-97-2.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR COLORLESS TO YELLOWISH LIQUID | [Melting point ]
-73 °C
| [Boiling point ]
128-130 °C(lit.)
| [density ]
1.094 g/mL at 25 °C(lit.)
| [vapor pressure ]
54-449hPa at 50-100℃ | [refractive index ]
n20/D 1.415(lit.)
| [Fp ]
84 °F
| [storage temp. ]
Flammables area | [solubility ]
52g/l | [form ]
Liquid | [color ]
Clear colorless to yellow | [PH]
3.4 (10g/l, H2O, 20℃) | [explosive limit]
2.3%(V) | [Water Solubility ]
52 g/L (20 ºC) | [Sensitive ]
Moisture Sensitive | [BRN ]
1733700 | [InChIKey]
CRZJPEIBPQWDGJ-UHFFFAOYSA-N | [LogP]
0.605 (est) | [CAS DataBase Reference]
97-97-2(CAS DataBase Reference) | [NIST Chemistry Reference]
Ethane, 2-chloro-1,1-dimethoxy-(97-97-2) | [EPA Substance Registry System]
97-97-2(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,F | [Risk Statements ]
R10:Flammable.
R22:Harmful if swallowed.
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R40:Limited evidence of a carcinogenic effect.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S16:Keep away from sources of ignition-No smoking .
S36:Wear suitable protective clothing .
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) . | [RIDADR ]
UN 1989 3/PG 3
| [WGK Germany ]
2
| [F ]
1 | [TSCA ]
Yes | [HazardClass ]
3 | [PackingGroup ]
III | [HS Code ]
29110000 | [Hazardous Substances Data]
97-97-2(Hazardous Substances Data) |
| Hazard Information | Back Directory | [Chemical Properties]
CLEAR COLORLESS TO YELLOWISH LIQUID | [Uses]
Chloroacetaldehyde dimethyl acetal can be used as a reactant to synthesize:
- 2-(chloromethyl)-4,7-dethyl-1,3-dioxepane
- 2-(chloromethyl)-5,6-benzo-1,3-dioxepane
- ketene dimethyl acetal
| [Preparation]
Chloroacetaldehyde dimethyl acetal is obtained by the stoichiometric reaction of vinyl acetate and chlorine in the presence of excess methanol. The specific steps are as follows:
186 ml (172 g = 2.0 mol) of vinyl acetate and 142 g (2.0 mol) of chlorine were simultaneously introduced into 324 ml of methanol with stirring and cooling at 0 ° to 2 ° within 1 hour. Then 50 ml of low boilers were distilled off over a 50 cm Vigreux column, then 19.8 g of an intermediate run of a batch which had been carried out in the same way were added, and finally 34 g of calcium oxide were added with stirring and cooling at 40 ° -50 ° C. within 30 minutes. After neutralization was complete, the reaction mixture was in the form of two separate liquid phases. After the layers had been separated off, the upper layer obtained was fractionated, 88 g of the forerunner, which mainly comprised methyl acetate and methanol, 19.8 g of the intermediate run, which mainly contained methanol, chloroacetaldehyde, chloroacetaldehyde mono and dimethylacetal, and the main fraction was 223.1 g of chloroacetaldehyde dimethylacetal ds 89.5% d. Th. Were obtained. If the lower layer formed after the calcium oxide addition is shaken twice with 100 ml of methyl acetate each time and the combined organic phases are distilled, 92.1% of theory. Th. Chloroacetaldehyde dimethyl acetal obtained. | [General Description]
Chloroacetaldehyde dimethyl acetal is a clear, colorless liquid. It reacts with hydroxythiol to form hydroxy acetal. | [Purification Methods]
Purify the acetal by fractional distillation. [Melhotra J Indian Chem Soc 36 4405 1959, Beilstein 1 IV 3134.] |
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