| Identification | More | [Name]
Methyl indole-3-carboxylate | [CAS]
942-24-5 | [Synonyms]
1H-INDOLE-3-CARBOXYLIC ACID METHYL ESTER
INDOLE-3-CARBOXYLIC ACID METHYL ESTER
METHYL 1H-INDOLE-3-CARBOXYLATE
METHYL-(3-INDOLCARBOXYLATE)
METHYL INDOLE-3-CARBOXYLATE
RARECHEM AH BS 0112
methyl indoline-3-carboxylate
Methylindole-3-Carboxylate99%
3-Indolecarboxylic acid methyl ester | [EINECS(EC#)]
618-347-7 | [Molecular Formula]
C10H9NO2 | [MDL Number]
MFCD00189407 | [Molecular Weight]
175.18 | [MOL File]
942-24-5.mol |
| Chemical Properties | Back Directory | [Appearance]
light brown amorphous powder | [Melting point ]
149-152 °C (lit.) | [Boiling point ]
306.47°C (rough estimate) | [density ]
1.1999 (rough estimate) | [refractive index ]
1.5060 (estimate) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
15.42±0.30(Predicted) | [color ]
Light Pink | [Water Solubility ]
Slightly soluble methanol and dimethyl sulfoxide. Insoluble in water. | [BRN ]
142023 | [InChI]
InChI=1S/C10H9NO2/c1-13-10(12)8-6-11-9-5-3-2-4-7(8)9/h2-6,11H,1H3 | [InChIKey]
QXAUTQFAWKKNLM-UHFFFAOYSA-N | [SMILES]
N1C2=C(C=CC=C2)C(C(OC)=O)=C1 | [CAS DataBase Reference]
942-24-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [HazardClass ]
IRRITANT | [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Chemical Properties]
light brown amorphous powder | [Uses]
Methyl indole-3-carboxylate is a reagent in the preaparation of oncrasin-1 derivatives which is a novel inhibitor of the C-terminal domain of RNA polymerase II. | [Definition]
ChEBI: Methyl indole-3-carboxylate is the methyl ester of indole-3-carboxylic acid. It has a role as a metabolite. It is a member of indoles and a methyl ester. It is functionally related to an indole-3-carboxylic acid. | [General Description]
Methyl indole-3-carboxylate (3-Methoxycarbonylindole, 3-Carbomethoxyindole, Methyl indolyl-3-carboxylate) has been extracted from the marine Streptomyces sp. 060524. Its crystal structure indicates the presence of inter-molecular N-H…O hydrogen bond. It is also obtained during the isolation of sorazinones A and B from Sorangium cellulosum strain Soce895. It undergoes regioselective dibromination with bromine in acetic acid to afford methyl 5,6-dibromoindole-3-carboxylate. |
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