| Identification | More | [Name]
1-Methylpyrazole | [CAS]
930-36-9 | [Synonyms]
1-METHYL-1H-PYRAZOLE
1-METHYLPYRAZOLE
AKOS PAO-1140
N-METHYLPYRAZOLE
N-MP
TRIS-1-PYRAZOLYLMETHANE
1H-Pyrazole, 1-methyl-
methylpyrazole
Pyrazole, 1-methyl-
1-Methylpyrazole,97%
1-Methyl-1H-pyrazole, 97+%
1-Methylpyrazole ,99% | [EINECS(EC#)]
618-896-2 | [Molecular Formula]
C4H6N2 | [MDL Number]
MFCD00144943 | [Molecular Weight]
82.1 | [MOL File]
930-36-9.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless to light yellow liquid | [Melting point ]
36.5°C (estimate) | [Boiling point ]
127 °C
| [density ]
0.988 g/mL at 20 °C(lit.)
| [refractive index ]
n20/D 1.477
| [Fp ]
35 °C
| [storage temp. ]
Flammables area | [Water Solubility ]
Soluble in water | [form ]
Liquid | [pka]
2.25±0.10(Predicted) | [color ]
Clear colorless to light yellow | [Detection Methods]
GC,NMR | [BRN ]
105207 | [InChI]
InChI=1S/C4H6N2/c1-6-4-2-3-5-6/h2-4H,1H3 | [InChIKey]
UQFQONCQIQEYPJ-UHFFFAOYSA-N | [SMILES]
N1(C)C=CC=N1 | [CAS DataBase Reference]
930-36-9(CAS DataBase Reference) | [NIST Chemistry Reference]
1-methylpyrazole(930-36-9) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R10:Flammable.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
UN 1993 3/PG 3
| [WGK Germany ]
3
| [F ]
10 | [HazardClass ]
3 | [PackingGroup ]
III | [HS Code ]
29331990 |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless to light yellow liquid | [Uses]
1-Methylpyrazole is a useful synthetic intermediate. It is used to synthesize heteroaryl(fluorophenyl)piperidinylindoles as α1 adrenoceptor antagonists. It is also used to prepare quinazoline derivatives as glucokinase activators. | [Definition]
ChEBI: A member of the class of pyrazoles that is the 1-methyl derivative of 1H-pyrazole. | [Synthesis]
1-Methylpyrazole was prepared by the condensation of 1,1,3,3-tetraethoxypropane with methylhydrazine[1]. | [References]
[1] Peggy W. Alley, David A. Shirley. “The Metalation of 1-Phenyl- and 1-Methylpyrazole with n-Butyllithium.” Journal of the American Chemical Society 80 23 (1958): 6271–6274.
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