Identification | Back Directory | [Name]
Chorionic gonadotrophin | [CAS]
9002-61-3 | [Synonyms]
HCG apl HGG LHA TSHA HUCG gonan physex riogon praedyn pregnyl profasi gonadex ambinon chorulon apoidina choragon chorigon predalon gravimun korotrin gonabion randonos pregnesin lutormone physostab coriantin follutein endocorion ferti-cept antelobine antophysin antuitrins HCG, HUMAN primogonyl synaphorin Aids072611 Aids-072611 HCG, INTACT anteparsine choriogonin apl(hormone) apl[hormone] prolan(bayer) glanduantin-ch gonadotraphonlh gonadyl-chorionic Choriogonin, HCG choriogonadotropin pregnancyurineextract gonadotropin,chorionic Choriogonadotropinalfa chorionicgonadotrophin CHORIONIC GONADOTROPIN pregnancyurine hormone beta chorionic gonadotropin gonadotropin,humanchorionic CHORIONIC GONADOTROPIN-ALPHA HUMAN CHORIONIC GONADOTROPIN CHORIONIC GONADOTROPIN HORSE CHORIONIC GONADOTROPIN HUMAN chorionicgonadotropichormone HUMAN CHORIONIC GONADOTROPHIN Humanchrorionicgonadotrophine gonadotrop(h)in,humanchorionic CHORIONIC GONADOTROPIN, U.S.P. Chorionic gonadotropin huMan (HCG) CHORIONIC GONADOTROPIN, HUMAN URINE CHORIONIC GONADOTROPHIN, HUMAN, INTACT CHORIONIC GONADOTROPIN HUMAN RECOMBINAN& CHORIONIC GONADOTROPIN FROM HUMAN & CHORIONIC GONADOTROPIN HUMAN,EMBRYO TEST ED CHORIONIC GONADOTROPHIN, HUMAN URINE, INTACT Chorionic gonadotropin human,Choriogonin, HCG Chorionic Gonadotropin, HumanUrine, Iodination Grade PURIFIEDHCG(CHORIONICGONADOTROPINFROMHUMAN*PREGNANCYURINE) CHORIONIC GONADOTROPIN (HCG)DEVELOPED IN RABBIT (3,500 IU/MG) Human Chorionic Gonadotropin (1 vial, 5,760 USP Units per package) Human Chorionic Gonadotropin (1 vial, 5,760 USP Units per package) (COLD SHIPMENT REQUIRED) | [EINECS(EC#)]
232-660-2 | [Molecular Formula]
C17H28 | [MDL Number]
MFCD00130797 | [MOL File]
9002-61-3.mol | [Molecular Weight]
232.404 |
Chemical Properties | Back Directory | [Appearance]
White or yellowish-white, amorphous powder. | [storage temp. ]
2-8°C
| [solubility ]
H2O: soluble1ML/vial | [form ]
lyophilized powder
| [color ]
White to off-white |
Raw materials And Preparation Products | Back Directory | [Raw materials]
Ethanol-->Sodium chloride-->Sodium acetate trihydrate-->Ammonium sulfate-->Acetamide-->Benzoic acid-->Aluminium potassium sulfate dodecahydrate-->Calcium acetate-->Trisodium phosphate-->TRIS BORATE EDTA BUFFER, 10X, DNASE, RNASE AND PROTEASE FREE, PH 8.3, FOR MOLECULAR BIOLOGY-->ACETALDEHYDE AMMONIA-->HEMOGLOBIN-->IGE, ANTI-HUMAN, GOAT, IGG FRAC, FITC, LQ-->Ethacridine lactate monohydrate |
Hazard Information | Back Directory | [Chemical Properties]
White or yellowish-white, amorphous powder. | [Uses]
Gonad-stimulating principle. | [Application]
Human chorionic gonadotropin (hCG) is a chemical produced by the trophoblast tissue, which is usually present in the early embryo and will eventually become part of the placenta. Measuring hCG levels helps to identify normal, pathological and miscarried pregnancies. Measuring hCG is also beneficial for many cancers including choriocarcinoma and extrauterine malignancies. | [Production Methods]
CG is produced in the chorion.
| [Brand name]
A.P.L. (Ferring Pharmaceuticals); Follutein (Bristol-Myers
Squibb); Pregnyl (Organon). | [General Description]
Glycoprotein hormone consisting of a 92-amino acid α-chain which is identical to that of LH, FSH, and TSH; and a distinct 149-amino acid β-chain. Produced by chorionic tissue and responsible for maintaining the corpus luteum during early pregnancy. Also produced by trophoblast cell neoplasms, which are marked by elevated free hCG β-chains and hyperglycosylated hCG. | [Biochem/physiol Actions]
Elevated levels of hCG is observed in trophoblastic cancer. hCG levels are indicators of pregnancy and β subunit is majorly present in urine samples. hCG isoform detection is useful in the diagnosis and management of trophoblastic related diseases including carcinomas. | [Clinical Use]
Choriogonadotropin alfa is obtained by rDNA technology and is biologically and chemically
identical to hCG of natural origin. It is used, like hCG of natural origin, for inducing ovulation in
women with anovulatory infertility. Following proper pretreatment with a GnRH antagonist or
superagonist to desensitize the pituitary, women participating in ART are treated with a folliclestimulating agent (e.g., menotropins) to effect the final maturation of the follicles within the
ovaries. Ultrasonograms are used to determine proper follicle maturation before the
administration of choriogonadotropin alfa to induce ovulation. A distinct advantage of this
product is that it can be self-administered by the patient via SC injection. | [Veterinary Drugs and Treatments]
The veterinary product’s labeled indication is for “parenteral use
in cows for the treatment of nymphomania (frequent or constant
heat) due to cystic ovaries.” It has been used for other purposes in
several species; refer to the Dosage section for more information. |
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