| Identification | More | [Name]
4-CHLORO-2-NITROPHENOL | [CAS]
89-64-5 | [Synonyms]
1-CHLORO-4-HYDROXY-3-NITROBENZENE
2-NITRO-4-CHLOROPHENOL
4-CHLORO-2-NITROPHENOL
AKOS BBS-00004667
O-NITRO-P-CHLOROPHENOL
4-chloro-2-nitro-pheno
o-nitro-p-chorophenol
4-Chloro-2-nitrophenol,98%,containsuptoca10%water
4-CHLORO-2-NITROPHENOL , CONTAINS UP TO CA 10% WATER
2-Nitro-4-chlorophenol,p-Chloro-o-nitrophenol | [EINECS(EC#)]
201-927-5 | [Molecular Formula]
C6H4ClNO3 | [MDL Number]
MFCD00007113 | [Molecular Weight]
173.55 | [MOL File]
89-64-5.mol |
| Chemical Properties | Back Directory | [Appearance]
yellow powder | [Melting point ]
85-87 °C(lit.) | [Boiling point ]
242.5±20.0 °C(Predicted) | [density ]
1.4914 (rough estimate) | [refractive index ]
1.5810 (estimate) | [solubility ]
dioxane: soluble0.5g/5mL, clear, faintly yellow to yellow | [form ]
powder to crystal | [pka]
pK1: 6.48 (25°C) | [color ]
Light yellow to Yellow to Orange | [BRN ]
2048031 | [CAS DataBase Reference]
89-64-5(CAS DataBase Reference) | [EPA Substance Registry System]
4-Chloro-2-nitrophenol (89-64-5) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
2811 | [WGK Germany ]
3
| [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29089990 |
| Questions And Answer | Back Directory | [Description]
4-Chloro-2-nitrophenol, is a kind of chloronitrophenols (CNPs), being widely used in the synthesis of dyes, drugs and pesticides. Furthermore, it can be used to produce 2-Amino-4-chloro-phenol.It has become a major group of environmental pollutants. 4-Chloro-2-nitrophenol has been detected in various industrial effluents. Therefore, it has also been used as a model compound for evaluation of biodegradation strategy using microbes.
| [Sources]
https://microbialcellfactories.biomedcentral.com/articles/10.1186/1475-2859-11-150
https://www.sciencedirect.com/science/article/pii/S0304389407009570
https://www.lookchem.com/4-Chloro-2-nitrophenol/
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| Hazard Information | Back Directory | [Chemical Properties]
yellow powder | [Uses]
Reduction of 4-Chloro-2-nitrophenol gives 2-amino-4- chlorophenol [95-85-2], and chlorination yields 2,4-dichloro-6-nitrophenol [609-89-2], which is reduced to 2-amino-4,6-dichlorophenol [527-62-8]. These substituted aminophenols are members of a large class of diazo components used for hydroxyazo dyes, which are important for wool and polyamide when converted to their chromium complexes. For the amine derived from the methyl ether of 4-Chloro-2-nitrophenol, 4- chloro-o-anisidine [93-50-5], the preferred route is methoxylation of 2,5-dichloronitrobenzene followed by reduction. 2-amino-4-chlorophenol reacts with phosgene to give 5- chlorobenzoxolinone which nitrates to the 6-nitro compound; the latter undergoes alkaline hydrolysis to 2-amino-4- chloro-5-nitrophenol. | [Production Methods]
2,5-Dichloronitrobenzene is hydrolyzed with 8 % aqueous sodium hydroxide at 120 – 130 ℃ under pressure.
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