| Identification | More | [Name]
FMOC-6-AMINOHEXANOIC ACID | [CAS]
88574-06-5 | [Synonyms]
6-(((9H-FLUOREN-9-YL)METHOXY)CARBONYLAMINO)HEXANOIC ACID
6-(FMOC-AMINO)CAPROIC ACID
6-(FMOC-AMINO)HEXANOIC ACID
9-FLUORENYLMETHOXYCARBONYL-6-AMINOCAPROIC ACID
9-FLUORENYLMETHOXYCARBONYL-EPSILON-AMINOHEXANOIC ACID
FMOC-6-ACA-OH
FMOC-6-AHX-OH
FMOC-6-AMINOCAPROIC ACID
FMOC-6-AMINOHEXANOIC ACID
FMOC-ACP(6)-OH
FMOC-ACP-OH
FMOC-AHX(6)-OH
FMOC-AMINOCAPROIC ACID
FMOC-EPSILON-ACP-OH
FMOC-EPSILON-AHX-OH
FMOC-EPSILON-AMINOCAPROIC ACID
FMOC-NH-(CH2)5-COOH
N-(9-FLUORENYLMETHYLOXYCARBONYL)-6-AMINOHEXANOIC ACID
N-(9-FLUORENYLMETHYLOXYCARBONYL)-EPSILON-AMINO-CAPROIC ACID
N-EPSILON-FMOC-AMINOHEXANOIC ACID | [Molecular Formula]
C21H23NO4 | [MDL Number]
MFCD00077045 | [Molecular Weight]
353.41 | [MOL File]
88574-06-5.mol |
| Chemical Properties | Back Directory | [Melting point ]
114 °C | [Boiling point ]
582.7±33.0 °C(Predicted) | [density ]
1.210±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
Soluble in water or 1% acetic acid | [form ]
Powder | [pka]
4.75±0.10(Predicted) | [color ]
White | [Water Solubility ]
Soluble in 1% acetic acid, water and 1mmol in 2mL DMF clearly soluble. | [BRN ]
5883220 | [CAS DataBase Reference]
88574-06-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [HazardClass ]
IRRITANT | [HS Code ]
29242990 |
| Hazard Information | Back Directory | [Description]
Fmoc-6-aminohexanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Fmoc-6-aminohexanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | [Chemical Properties]
White powder | [Uses]
Fmoc-6-aminohexanoic acid, is an amino acid derivative used in chemical synthesis and peptide chemistry. | [reaction suitability]
reaction type: Fmoc solid-phase peptide synthesis |
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