Identification | Back Directory | [Name]
Fmoc-9-Amino-4,7-Dioxanonanoic acid | [CAS]
872679-70-4 | [Synonyms]
Fmoc-AEEP Fmoc-PEG2- CH2CH2COOH Fmoc-N-amido-PEG2-acid FMoc-NH-PEG2-CH2CH2COOH Fmoc-PEG2-propionic acid Fmoc-AEEP-OH≥ 98% (HPLC) Fmoc-N-amido-PEG2-acid 99% Fmoc-9-amino-4,7-dioxonanoic acid 9-(Fmoc-amino)-4,7-dioxanonanoic Acid 3-[2-[2-(Fmoc-amino)ethoxy]ethoxy]propionic Acid 9-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-4,7-dioxanonanoic Acid 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10-trioxa-4-azatridecan-13-oic acid 4,7,12-Trioxa-10-azatridecanoic acid, 13-(9H-fluoren-9-yl)-11-oxo- 9-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-4,7-dioxanonanoicAcid> 2,7,10-Trioxa-4-azatridecan-13-oic acid, 1-(9H-fluoren-9-yl)-3-oxo- 3-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]propanoic acid 3-[2-[2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]ethoxy]ethoxy]propionic Acid 3-[2-[2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]ethoxy]ethoxy]propanoic acid | [Molecular Formula]
C22H25NO6 | [MDL Number]
MFCD08064306 | [MOL File]
872679-70-4.mol | [Molecular Weight]
399.437 |
Chemical Properties | Back Directory | [Melting point ]
95.0 to 99.0 °C | [Boiling point ]
621.0±50.0 °C(Predicted) | [density ]
1.243±0.06 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
soluble in Methanol | [form ]
powder to crystal | [pka]
4.28±0.10(Predicted) | [color ]
White to Almost white |
Hazard Information | Back Directory | [Description]
Fmoc-N-amido-PEG2-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | [Chemical Properties]
White crystalline powder | [Uses]
Fmoc-AEEP-OH is used in preparation of glucose-responsive insulin conjugates. |
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