Identification | More | [Name]
4-Amino-1-Boc-piperidine | [CAS]
87120-72-7 | [Synonyms]
1-BOC-4-AMINOPIPERIDINE 1-BOC-4-PIPERIDINAMINE 1-BUTYLOXYCARBONYL-4-AMINO-PIPERIDINE 1-N-BOC-4-AMINOPIPERIDINE 1-PIPERIDINECARBOXYLIC ACID, 4-AMINO-,1,1-DIMETHYLETHYL ESTER 1-T-BUTOXYCARBONYL-4-AMINOPIPERIDINE 1-tert-Butoxycarbonyl-4-amino-piperidine 4-AMINO-1-BOC-PIPERIDINE 4-AMINO-1-N-BOC-PIPERIDINE 4-AMINO-1-TERT-BUTOXYCARBONYL-PIPERIDINE 4-AMINOPIPERIDINE, 1-BOC PROTECTED 4-AMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER BOC-PIP(4-NH2) BUTTPARK 90\06-10 CHEMBRDG-BB 4003509 N-1-BOC-4-AMINOPIPERIDINE N-BOC-4-AMINOPERIDINE N-BOC-4-AMINOPIPERIDINE N-TERT-BUTOXYCARBONYL-4-AMINOPIPERIDINE TERT-BUTYL 4-AMINO-1-PIPERIDINECARBOXYLATE | [EINECS(EC#)]
1312995-182-4 | [Molecular Formula]
C10H20N2O2 | [MDL Number]
MFCD01076201 | [Molecular Weight]
200.28 | [MOL File]
87120-72-7.mol |
Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powder | [Melting point ]
50°C | [Boiling point ]
80/0.037mm | [density ]
1.041±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
Crystalline Powder, Crystals and/or Chunks | [pka]
10.10±0.20(Predicted) | [color ]
White to pale yellow to beige | [Water Solubility ]
Insoluble in water. | [Sensitive ]
Air Sensitive | [Detection Methods]
GC | [InChI]
InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-8(11)5-7-12/h8H,4-7,11H2,1-3H3 | [InChIKey]
LZRDHSFPLUWYAX-UHFFFAOYSA-N | [SMILES]
N1(C(OC(C)(C)C)=O)CCC(N)CC1 | [CAS DataBase Reference]
87120-72-7(CAS DataBase Reference) | [Storage Precautions]
Store under nitrogen |
Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed. R37/38:Irritating to respiratory system and skin . R41:Risk of serious damage to eyes. R36/37/38:Irritating to eyes, respiratory system and skin . R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . S22:Do not breathe dust . | [RIDADR ]
3259 | [WGK Germany ]
2
| [F ]
10-34 | [Hazard Note ]
Irritant | [TSCA ]
N | [HazardClass ]
8 | [HazardClass ]
IRRITANT | [PackingGroup ]
Ⅲ | [HS Code ]
29333990 |
Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powder | [Uses]
4-Amino-1-Boc-piperidine is a chemical reagent used in the preparation of pharmaceutical compounds. Used in the synthesis of bromodomain inhibitors as well as HepG2 cell cycle inhibitors used in anti-tumor therapy. Also employed in a microwave-assisted solid-phase synthesis of N-substituted piperidines via direct annulation of primary amines with resin-bound dimesylates. | [Application]
4-Amino-1-Boc-piperidine is a pharmaceutical intermediate is applied in the treatment of anti-tumor and other drugs. It is an important fine chemical intermediate and has a wide range of uses in the pharmaceutical industry.
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