Identification | More | [Name]
5-Aminolevulinic acid methyl ester hydrochloride | [CAS]
79416-27-6 | [Synonyms]
3-AMINOACETYLPROPIONIC ACID METHYL ESTER HYDROCHLORIDE 5-AMINO-4-OXO-N-VALERIC ACID METHYL ESTER HYDROCHLORIDE 5-AMINO-4-OXOPENTANOIC ACID METHYL ESTER HYDROCHLORIDE 5-AMINOLEVULINIC ACID METHYL ESTER HYDROCHLORIDE ALA METHYL ESTER HYDROCHLORIDE D-AMINOLEVULINIC ACID METHYL ESTER HYDROCHLORIDE DELTA-AMINOLEVULINIC ACID METHYL ESTER HYDROCHLORIDE METHYL 5-AMINOLEVULINATE HYDROCHLORIDE METHYL DELTA-AMINOLEVULINATE HYDROCHLORIDE methyl 5-amino-4-oxovalerate hydrochloride DELTA-AMINOLEVULINIC ACID METHYL ESTERHY DROCHLORID 5-amino-4-oxopentanoic acid methyl ester methyl δ-aminolevulinate hydrochloride 5-Aminolevulinic acid methyl ester HCl Methyl 5-amino-4-oxopentanoate hydrochloride H-TIC(OTBU)-OH APTS 5-AMINOLEVULINIC ACID METHYL ESTER HYDROCHLORIDE 98+% 5-Amino-4-oxovaleric Acid Methyl Ester Hydrochloride 5-Amino-4-oxopentanoic acid methyl ester, 5-Aminolevulinic acid methyl ester 4-(Methoxycarbonyl)-2-oxobutylamine·hydrochloride | [EINECS(EC#)]
279-151-1 | [Molecular Formula]
C6H12ClNO3 | [MDL Number]
MFCD00012868 | [Molecular Weight]
181.62 | [MOL File]
79416-27-6.mol |
Chemical Properties | Back Directory | [Melting point ]
119-121° | [storage temp. ]
2-8°C
| [solubility ]
DMSO (Slightly), Methanol (Slightly), Water (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Water Solubility ]
very faint turbidity | [Sensitive ]
Light Sensitive/Hygroscopic | [Stability:]
Hygroscopic | [InChIKey]
UJYSYPVQHFNBML-UHFFFAOYSA-N | [CAS DataBase Reference]
79416-27-6(CAS DataBase Reference) |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [HS Code ]
29225090 |
Hazard Information | Back Directory | [Chemical Properties]
5-Aminolevulinic acid methyl ester hydrochloride is white powder
| [Uses]
5-Aminolevulinic acid methyl ester hydrochloride is used in photodynamic therapy.
| [Definition]
ChEBI: The hydrochloride salt of methyl 5-aminolevulinate. A prodrug, it is metabolised to protoporphyrin IX, a photosensitizer, and is used in the photodynamic treatment of non-melanoma skin cancer (including basal cell carcinoma). Topical application results in
an accumulation of protoporphyrin IX in the skin lesions to which the cream has been applied. Subsequent illumination with red light results in the generation of toxic singlet oxygen that destroys cell membranes and thereby kills the tumour cells. | [Brand name]
Metvixia
(PhotoCure, Norway). | [Biochem/physiol Actions]
Methyl δ-aminolevulinate (methyl-ALA, MAL) and 5-Aminolevulinic acid (5-ALA) are commonly used in photosentizer reagents for photodynamic therapy to treat conditions such as Acne vulgaris and hypertrophic scarring. |
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