| Identification | Back Directory | [Name]
Bis(NHS)PEG5 | [CAS]
756526-03-1 | [Synonyms]
756526-03-1
Bis(NHS)PEG5
BIS-PEG5-NHS
NHS-PEG5-NHS
PEG5 BIS-NHS ESTER
Bis-PEG5-NHS ester
Bis-PEG6-NHS ester
Bis-dPEG5-NHS ester
Bis-dPEG(R)5-NHS ester
Bis(3-PEG4)propionic acid N-hydroxysuccinimide diester
Di(N-succinimidyl) 4,7,10,13,16-Pentaoxanonadecanedioate
4,7,10,13,16-Pentaoxanonadecanedioic Acid Di(N-succinimidyl) Ester
Bis(2,5-dioxopyrrolidin-1-yl) 4,7,10,13,16-pentaoxanonadecane-1,19-dioate
4,7,10,13,16-Pentaoxanonadecanedioic acid, 1,19-bis(2,5-dioxo-1-pyrrolidinyl) ester | [Molecular Formula]
C22H32N2O13 | [MDL Number]
MFCD11041118 | [MOL File]
756526-03-1.mol | [Molecular Weight]
532.51 |
| Hazard Information | Back Directory | [Description]
Bis-PEG5-NHS ester is a PEG linker containing two NHS ester groups. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. | [Uses]
Bis(NHS)PEG5 is used in targeting M2-like tumor-associated macrophages by using melittin-based pro-apoptotic peptide conjugates with anti-cancer drugs, | [General Description]
By contrast to typical PEG reagents that contain heterogeneous mixtures of different PEG chain lengths, this PEG reagent is a homogeneous compound of defined molecular weight and spacer arm length, providing greater precision in optimization and characterization of crosslinking applications. Homobifunctional crosslinkers containing N-hydroxysuccinimide (NHS) esters are often used for low-resolution 3-D studies of protein structure and protein interaction analysis. |
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