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ChemicalBook--->CAS DataBase List--->1334170-02-3

1334170-02-3

1334170-02-3 Structure

1334170-02-3 Structure
IdentificationBack Directory
[Name]

alpha, oMega-DisucciniMidyl hexaethylene glycol
[CAS]

1334170-02-3
[Synonyms]

NHS-PEG6-NHS
Bis-PEG7-NHS ester
α,ω-disuccinimidyl hexaethylene glycol
alpha, oMega-DisucciniMidyl hexaethylene glycol
4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid, 1,25-bis(2,5-dioxo-1-pyrrolidinyl) ester
[Molecular Formula]

C26H40N2O15
[MDL Number]

MFCD18916987
[MOL File]

1334170-02-3.mol
[Molecular Weight]

620.6
Chemical PropertiesBack Directory
[solubility ]

Soluble in DMSO, DCM, DMF
[form ]

Viscous Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Description]

Bis-PEG7-NHS ester is a PEG linker containing two NHS ester groups. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
[Biological Activity]

Bis-PEG7-NHS ester is a PROTAC bridge, belonging to the PEG class and the Alkyl/ether class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).
[target]

Cleavable

PEGs

Alkyl/ether

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