| Identification | More | [Name]
p-Hydroxy-cinnamic acid | [CAS]
7400-08-0 | [Synonyms]
3-(4-HYDROXYPHENYL)ACRYLIC ACID
4-COUMARIC ACID
4-HYDROXYCINNAMIC ACID
AKOS 221-47
AKOS BAR-2479
COUMARIC ACID, TRANS-P-
LABOTEST-BB LT00452637
P-COUMARIC ACID
P-CUMARIC ACID
PHCA
P-HYDROXYCINNAMIC ACID
P-HYDROXYL CINNAMIC ACID
RARECHEM BK HW 0163
TRANS-4-COUMARIC ACID
TRANS-4-HYDROXYCINNAMIC ACID
TRANS-P-COUMARIC ACID
TRANS-P-CUMARIC ACID
(2E)-3-(4-Hydroxyphenyl)-2-propenoic acid
3-(4-Hydroxyphenyl)-2-propenoic acid
3-(4-hydroxyphenyl)-2-propenoicaci | [EINECS(EC#)]
231-000-0 | [Molecular Formula]
C9H8O3 | [MDL Number]
MFCD00004399 | [Molecular Weight]
164.16 | [MOL File]
7400-08-0.mol |
| Chemical Properties | Back Directory | [Appearance]
Light yellow to beige crystalline powder | [Melting point ]
214 °C (dec.)(lit.)
| [Boiling point ]
251.61°C (rough estimate) | [density ]
1.2132 (rough estimate) | [refractive index ]
1.5380 (estimate) | [storage temp. ]
Store below +30°C. | [solubility ]
Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
4.65±0.10(Predicted) | [color ]
White to Off-White | [Stability:]
Light Sensitive | [InChI]
InChI=1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12) | [InChIKey]
NGSWKAQJJWESNS-UHFFFAOYSA-N | [SMILES]
C(O)(=O)C=CC1=CC=C(O)C=C1 | [LogP]
1.790 | [CAS DataBase Reference]
7400-08-0(CAS DataBase Reference) | [NIST Chemistry Reference]
2-Propenoic acid, 3-(4-hydroxyphenyl)-(7400-08-0) | [EPA Substance Registry System]
7400-08-0(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S22:Do not breathe dust . | [WGK Germany ]
2
| [RTECS ]
GD9095000
| [HS Code ]
2918 29 00 | [Safety Profile]
Moderarely toxic by
intraperitoneal route. Experimental
reproductive effects. When heated to
decomposition it emits acrid smoke and
fumes. See also COUMARIN |
| Hazard Information | Back Directory | [Hazard]
Moderately toxic. | [Chemical Properties]
Light yellow to beige crystalline powder | [Uses]
p-Coumaric Acid is the hydroxy derivative of Cinnamic Acid with antioxidant properties. p-Coumaric acid is a is a major component of lignocellulose. Studies suggest that p-Coumaric Acid may reduce the
risk of cancer by reducing the formation of carcinogenic nitrosamines. | [Application]
p-Hydroxycinnamic acid is mainly used as an intermediate in the pharmaceutical and perfume industries. It can react with dimethyl sulfate to produce p-anisaldehyde, react with acetaldehyde to produce p-hydroxycinnamaldehyde, and further oxidize it to produce cinnamic acid. This product can be directly oxidized to produce 4-Hydroxybenzoic acid and reduction to produce 4-Hydroxybenzyl alcohol. | [Definition]
ChEBI: A coumaric acid in which the hydroxy substituent is located at C-4 of the phenyl ring. | [storage]
Store at -20°C |
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