| Identification | More | [Name]
CHLOROMETHYL PHENYL SULFIDE | [CAS]
7205-91-6 | [Synonyms]
ALPHA-CHLOROTHIOANISOLE
CHLOROMETHYL PHENYL SULFIDE
CHLOROMETHYL PHENYL SULPHIDE
Chlorothioanisole
[(chloromethyl)thio]benzene
ALPHA-CHLOROTHIOANISOLE 95+%
Benzene, (chloromethyl)thio-
(phenylthio)methyl chloride
Chloromethyl phenyl sulphide 98%
CHLOROMETHYL PHENYL SULLFIDE, 97%
(chloromethyl)(phenyl)sulfane
Phenyl(chloromethyl) sulfide | [EINECS(EC#)]
230-579-7 | [Molecular Formula]
C7H7ClS | [MDL Number]
MFCD00000921 | [Molecular Weight]
158.65 | [MOL File]
7205-91-6.mol |
| Chemical Properties | Back Directory | [Boiling point ]
66 °C/0.2 mmHg (lit.) | [density ]
1.184 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.594(lit.)
| [Fp ]
214 °F
| [storage temp. ]
Refrigerator | [solubility ]
sol most organic solvents; insol H2O | [form ]
Liquid | [color ]
Clear colorless to pale yellow | [Sensitive ]
Stench | [BRN ]
1617369 | [InChIKey]
LLSMWLJPWFSMCP-UHFFFAOYSA-N | [CAS DataBase Reference]
7205-91-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S24/25:Avoid contact with skin and eyes . | [RIDADR ]
UN 3334 | [WGK Germany ]
3
| [F ]
10-13 | [Hazard Note ]
Stench | [HazardClass ]
4.1 | [PackingGroup ]
III | [HS Code ]
29309099 |
| Hazard Information | Back Directory | [Uses]
Reagent for the high-yield thiomethylation of O-silylated lactone and ester enolates in the synthesis of α-methylene lactones and esters. | [Uses]
Reagent for the high-yield thiomethylation of O-silylated lactone and ester enolates in the synthesis of α-methylene lactones and esters.1 | [Synthesis]
The two most convenient methods of chloromethyl phenyl sulfide are the reaction of Thioanisole with Sulfuryl Chloride and the reaction of Thiophenol with bromochloromethane using 1,8-Diazabicyclo[5.4.0]undec-7-ene or an alkali metal hydroxide as the base.
| [storage]
Chloromethyl phenyl sulfideshould be handled in a well-ventilated fume hood and kept cooled. Freshly prepared material can be stored at 0-5 °C without any appreciable decomposition. It is advisable to use freshly prepared or distilled material for reactions.
| [Purification Methods]
Dissolve the sulfide in CH2Cl2 or CCl4 and dry it (CaCl2), or pass it through a tube of CaCl2 and distil it using a fractionating column. Harmful vapours. It gives the sulfone [7205-98-3] (b 130o/1mm and m 53o from EtOH) [Beilstein 6 IV 1507] on oxidation with permonophthalic acid. [B.hme et al. Justus Liebigs Ann Chem 563 54 64 1949.] [Beilstein 6 III 1002.] |
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