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ChemicalBook--->CAS DataBase List--->6792-09-2

6792-09-2

6792-09-2 Structure

6792-09-2 Structure
IdentificationBack Directory
[Name]

Mesaconine
[CAS]

6792-09-2
[Synonyms]

Mesaconine
product/155130
Aconitane-3,8,13,14,15-pentol, 1,6,16-trimethoxy-4-(methoxymethyl)-20-methyl-, (1α,3α,6α,14α,15α,16β)-
(1alpha,3alpha,6alpha,14alpha,15alpha,16beta)-1,6,16-Trimethoxy-4-(methoxymethyl)-20-methyl-aconitane-3,8,13,14,15-pentol
[Molecular Formula]

C24H39NO9
[MDL Number]

MFCD29917565
[MOL File]

6792-09-2.mol
[Molecular Weight]

485.57
Chemical PropertiesBack Directory
[Boiling point ]

617.1±55.0 °C(Predicted)
[density ]

1.44±0.1 g/cm3(Predicted)
[storage temp. ]

4°C, sealed storage, away from moisture and light
[solubility ]

Aqueous Acid (Slightly), Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

12.22±0.70(Predicted)
[color ]

White
[Stability:]

Moisture Sensitive
Hazard InformationBack Directory
[Uses]

New use of neoaconitrile in the preparation of medicaments for preventing and/or treating myocardial fibrosis and chronic heart failure caused by myocardial fibrosis
[Biological Activity]

Mesaconinean, the active ingredient extracted from Aconitum carmichaelii Debx., has cardiovascular effects.
[Pharmacology]

1) Inhibit or reverse myocardial tissue fibrosis; 2) Improve abnormal cardiac remodeling; 3) Improve cardiac dysfunction; 4) Improve the survival rate of mice with chronic heart failure caused by myocardial fibrosis; 5) Fight against myocardial tissue inflammation; 6 ) Inhibition of cardiomyocyte apoptosis; 7) Myocardial enzyme activity in dead mice, and its mechanism of action is related to inhibiting myocardial tissue inflammation and fibrosis caused by adriamycin and resisting cardiomyocyte apoptosis.
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