| Identification | Back Directory | [Name]
OXIDIZED NIFEDIPINE | [CAS]
67035-22-7 | [Synonyms]
B 4759
BAY-b-4759
Dehydro Nifedipine
Nitrophenyl nifedipine
Nifedipine Nitrophenylpyridine Analog
dimethyl2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate
dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate
2,6-Dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylic acid dimethyl ester
4-(2-Nitrophenyl)-2,6-dimethylpyridine-3,5-dicarboxylic acid dimethyl ester
2,6-Dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3,5-Dimethyl Ester | [Molecular Formula]
C17H16N2O6 | [MDL Number]
MFCD00153847 | [MOL File]
67035-22-7.mol | [Molecular Weight]
344.319 |
| Hazard Information | Back Directory | [Chemical Properties]
Pale Yellow Solid | [Uses]
The main Nifedipine metabolite in human plasma | [Description]
Dehydro nifedipine is an active metabolite of nifedipine (Item No. 11106), a calcium channel blocker present in formulations used to treat hypertension and angina.1,2,3,4 Dehydro nifedipine is formed when nifedipine is metabolized by the cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5.2 Dehydro nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM.1 | [Definition]
ChEBI: Dehydronifedipine is a phenylpyridine. | [Biochem/physiol Actions]
CYP3A4 nifedipine metabolite. Nifedipine (parent compound) is an antianginal and antihypertensive agent. | [storage]
Store at -20°C |
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