| Identification | More | [Name]
3-ETHYL-3-METHYLGLUTARIMIDE | [CAS]
64-65-3 | [Synonyms]
2,6-DIOXO-4-METHYL-4-ETHYLPIPERIDINE
3-ETHYL-3-METHYLGLUTARIMIDE
3-METHYL-3-ETHYLGLUTARIMIDE
4-ETHYL-4-METHYL-2,6-PIPERIDINEDIONE
BEMEGRIDE
BETA-ETHYL-BETA-METHYLGLUTARIMIDE
B-METHYL-B-ETHYLGLUTARIMIDE
EUKRATON
METHETHARIMIDE
NP-13
2,6-Piperidinedione, 4-ethyl-4-methyl-
3,3-Methylethylilotarimide
3-ethyl-3-methyl-glutarimid
4-Ethyl-4-methyl-2,6-dioxopiperidine
4-ethyl-4-methyl-6-piperidinedione
4-Methyl-4-ethyl-2,6-dioxopiperidine
Agipnon
Ahypnon
Antibarbi
Bemegrid | [EINECS(EC#)]
200-588-0 | [Molecular Formula]
C8H13NO2 | [MDL Number]
MFCD00006673 | [Molecular Weight]
155.19 | [MOL File]
64-65-3.mol |
| Chemical Properties | Back Directory | [Appearance]
white to off-white flakes or powder | [Melting point ]
126-127 °C(lit.) | [Boiling point ]
279°C (rough estimate) | [density ]
1.1174 (rough estimate) | [refractive index ]
1.4860 (estimate) | [storage temp. ]
−20°C
| [solubility ]
DMSO:31.0(Max Conc. mg/mL);199.76(Max Conc. mM)
Ethanol:31.0(Max Conc. mg/mL);199.76(Max Conc. mM) | [Water Solubility ]
Soluble in water | [form ]
powder
| [pka]
pKa 11.7 (Uncertain) | [color ]
white
| [Merck ]
1027 | [CAS DataBase Reference]
64-65-3(CAS DataBase Reference) | [EPA Substance Registry System]
Bemegride (64-65-3) |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S22:Do not breathe dust .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2811 6.1/PG 2
| [WGK Germany ]
3
| [RTECS ]
MA4550000
| [HazardClass ]
6.1(a) | [PackingGroup ]
II | [HS Code ]
2933399990 | [Safety Profile]
Poison by ingestion,
intravenous, intraperitoneal, intramuscular,
subcutaneous, and parented routes. Human
systemic effects by ingestion: wakefulness,
hallucinations, distorted perceptions, toxic
psychosis. An analeptic, central nervous
system stimulant; used to counteract
barbiturate poisoning. When heated to
decomposition it emits toxic fumes of NOx. | [Toxicity]
LD50 in male mice (mg/kg): 20.1 ±1.41 i.v., 43.0 ±1.8 s.c.; LD50 in male rats (mg/kg): 16.3 ±1.24 i.v., 23.5 ±1.67 i.p (Hahn, Oberdorf) |
| Hazard Information | Back Directory | [General Description]
White crystalline solid. Sublimes at 212°F and 200 mm pressure. | [Reactivity Profile]
BEMEGRIDE(64-65-3) is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx). | [Air & Water Reactions]
Insoluble in water. | [Health Hazard]
ACUTE/CHRONIC HAZARDS: When heated to decomposition it emits toxic fumes. | [Fire Hazard]
Flash point data for this chemical are not available. BEMEGRIDE is probably not flammable. | [Chemical Properties]
white to off-white flakes or powder | [Uses]
CNS stimulant;GABA antagonist | [Definition]
ChEBI: 4-ethyl-4-methylpiperidine-2,6-dione is a member of piperidones. | [Brand name]
Megimide
(Abbott). |
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