| Identification | More | [Name]
4-Methoxystyrene | [CAS]
637-69-4 | [Synonyms]
1-METHOXY-4-VINYL-BENZENE
4-METHOXYSTYRENE
4-VINYLANISOLE
P-METHOXYSTYRENE
1-ethenyl-4-methoxybenzene
4-Vinylanisol
Anisole, p-vinyl-
p-Vinylanisole
4-METHOXYSTYRENE, STAB.
4-Methoxystyrene,98%
4-Methoxystyrene, stabilized, 96%
p-methoxystyrene,1-ethenyl-4-methoxy-benzene,p-vinylanisole
PARA-METHOXYSTYRENE
vinylanisole
4-Methoxystyrene, (Stabilized with 4-t-Butylcatechol)
4-Methoxystyrene, 98%, stab. with 0.1% 4-tert-butylcatechol
4-Methoxystyrene (stabilized with TBC)
(4-Methoxyphenyl)ethene
p-Anisylethylene
4-Methoxystyrene, 96%, stabilized | [EINECS(EC#)]
211-298-9 | [Molecular Formula]
C9H10O | [MDL Number]
MFCD00008619 | [Molecular Weight]
134.18 | [MOL File]
637-69-4.mol |
| Safety Data | Back Directory | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [HS Code ]
29093090 |
| Hazard Information | Back Directory | [Description]
4-Methoxystyrene (Para-methoxystyrene) is an important chemical raw material, can replace styrene compounds, and is widely applied to various fields such as a light polymerization inhibitor, a material, a medical intermediate, a pesticide, an adhesive, a coating, a sun-screening agent and the like. Besides, the p-methoxystyrene can be used as a polymerization monomer to synthesize polymers with different structures, and the synthesized polymer contains a protecting group which is easily subjected to acidolysis by light so that the p-methoxystyrene can be used as an excellent corrosion-resistant material to be applied to the electronic information industry. | [Chemical Properties]
CLEAR COLOURLESS LIQUID | [Uses]
4-Methoxystyrene is employed in the ferric chloride-catalyzed addition of activated methylenes to styrenes. It acts as a monomer in polymerization reactions. Further, it is used to prepare 1,1,2,2-Tetracyano-3-(p-methoxyphenyl)cyclobutane by reacting with ethenetetracarbonitrile. | [Synthesis Reference(s)]
Chemistry Letters, 13, p. 1897, 1984
The Journal of Organic Chemistry, 52, p. 422, 1987 DOI: 10.1021/jo00379a020
Tetrahedron Letters, 35, p. 8773, 1994 DOI: 10.1016/S0040-4039(00)78494-2 | [Synthesis]
The current methods for synthesizing 4-Methoxystyrene mainly comprise:
P-methoxy styrene is prepared by taking p-methoxy benzyl alcohol as a raw material and reacting with triphenylphosphine, formaldehyde and hydrobromic acid through the Wittig reaction.
P-methoxyacetophenone is used as a raw material, reduced to 1- (4-methoxyphenyl) ethanol by potassium borohydride, esterified with excessive potassium bisulfate in cyclohexane to generate sulfonic acid-1- (4-methoxyphenyl) ethyl ester, and finally subjected to elimination reaction to obtain 4-Methoxystyrene.
In 2021, an invention discloses a method for synthesizing 4-methoxystyrene, which comprises the steps of using p-methoxyacetophenone as a raw material, firstly carrying out hydrogenation reduction to generate 1- (4-methoxyphenyl) ethanol, then carrying out dehydration elimination reaction to obtain a crude product, and finally rectifying to obtain the 4-methoxystyrene. The invention adopts a catalytic hydrogenation method to get the intermediate 1- (4-methoxyphenyl) ethanol. The reaction selectivity of the step is excellent and can reach 98-99%, and meanwhile, hydrogen is used as a cleaning gas so that environmental pollution is avoided and industrial production is facilitated. |
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