Identification | More | [Name]
DIETHYL 1,4-DIHYDRO-2,4,6-TRIMETHYL-3,5-PYRIDINEDICARBOXYLATE | [CAS]
632-93-9 | [Synonyms]
1,4-DIHYDRO-2,4,6-TRIMETHYL-3,5-PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER 3,5-DICARBETHOXY-1,4-DIHYDRO-2,4,6-TRIMETHYLPYRIDINE 3,5-DIETHOXYCARBONYL-1,4-DIHYDRO-2,4,6-COLLIDINE DIETHYL 1,4-DIHYDRO-2,4,6-TRIMETHYL-3,5-PYRIDINEDICARBOXYLATE DIETHYL 1,4-DIHYDRO-2,4,6-TRIMETHYLPYRIDINE-3,5-DICARBOXYLATE 5-pyridinedicarboxylicacid,1,4-dihydro-2,4,6-trimethyl-diethylester Dicarbethoxydihydrocollidine diethyl dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate 3,5-dicarbethoxy-1,4-dihydrocollidine, DDC 1,4-Dihydro-2,4,6-collidine-3,5-dicarboxylic acid diethyl ester 1,4-Dihydro-2,4,6-trimethylpyridine-3,5-dicarboxylic acid diethyl ester 1,4-Dihydro-3,5-dicarbethoxycollidine 3,5-Bis(ethoxycarbonyl)-1,4-dihydrocollidine Diethyl 1,4-dihydro-s-collidine-3,5-dicarboxylate | [EINECS(EC#)]
211-188-0 | [Molecular Formula]
C14H21NO4 | [MDL Number]
MFCD00005950 | [Molecular Weight]
267.32 | [MOL File]
632-93-9.mol |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
US7979375 | [HS Code ]
2933.39.9200 |
Hazard Information | Back Directory | [Description]
Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate (DDC) inhibits heme production by inhibiting ferrochelatase, the enzyme that catalyzes the addition of Fe2+ to protoporphyrin IX to create heme B.1 Chronic DDC administration induces Mallory-Denk body formation, a feature of alcoholic and non-alcoholic hepatitis, and reduces IL-12A methylation in mouse liver.2,3 | [Chemical Properties]
almost white crystalline powder | [Uses]
Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate was used to induce Mallory-Denk body formation in mice in vivo. | [Definition]
ChEBI: A dihydropyridine that is 2,4,6-trimethyl-1,4-dihydropyridine substituted by ethoxycarbonyl groups at positions 3 and 5. | [Biochem/physiol Actions]
Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate blocks the heme synthesis and prevents the induction of hepatic heme oxygenase-1 in mice. | [Purification Methods]
Crystallise the ester from hot EtOH/water mixture. [Beilstein 22 H 147, 22 I 529, 22 II 100, 22 III/IV 1594.] |
Spectrum Detail | Back Directory | [Spectrum Detail]
DIETHYL 1,4-DIHYDRO-2,4,6-TRIMETHYL-3,5-PYRIDINEDICARBOXYLATE(632-93-9)MS DIETHYL 1,4-DIHYDRO-2,4,6-TRIMETHYL-3,5-PYRIDINEDICARBOXYLATE(632-93-9)1HNMR DIETHYL 1,4-DIHYDRO-2,4,6-TRIMETHYL-3,5-PYRIDINEDICARBOXYLATE(632-93-9)IR1 DIETHYL 1,4-DIHYDRO-2,4,6-TRIMETHYL-3,5-PYRIDINEDICARBOXYLATE(632-93-9)IR2 DIETHYL 1,4-DIHYDRO-2,4,6-TRIMETHYL-3,5-PYRIDINEDICARBOXYLATE(632-93-9)Raman
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Well-known Reagent Company Product Information | Back Directory | [Acros Organics]
Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate, 99%(632-93-9) | [Sigma Aldrich]
632-93-9(sigmaaldrich) | [TCI AMERICA]
3,5-Diethoxycarbonyl-1,4-dihydro-2,4,6-collidine,>98.0%(GC)(632-93-9) |
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