| Identification | More | [Name]
Hexyl salicylate | [CAS]
6259-76-3 | [Synonyms]
HEXYL 2-HYDROXYBENZOATE
HEXYL SALICYLATE
HEXYL SALICYLATE, N-
N-HEXYL-2-HYDROXYBENZOATE
N-HEXYL ORTHO HYDROXY BENZOATE
N-HEXYL SALICYLATE
O-HYDROXYBENZOIC ACID N-HEXYL ESTER
SALICYLIC ACID N-HEXYL ESTER
1-hexylsalicylate
2-hydroxy-benzoicacihexylester
Benzoic acid, 2-hydroxy-, hexyl ester
Benzoicacid,2-hydroxy-,hexylester
Hexyl salicilate
Salicylic acid, hexyl ester
salicylicacid,hexylester
2-Hydroxybenzoic acid hexyl ester
HEXYL SALICYLATE 98+%
SALICYLIC ACID N-HEXYL ESTER 5%
Hexylsalicylat | [EINECS(EC#)]
228-408-6 | [Molecular Formula]
C13H18O3 | [MDL Number]
MFCD00036487 | [Molecular Weight]
222.28 | [MOL File]
6259-76-3.mol |
| Chemical Properties | Back Directory | [Boiling point ]
290 °C (lit.) | [density ]
1.04 g/mL at 25 °C(lit.)
| [vapor pressure ]
0.077Pa at 23℃ | [refractive index ]
n20/D 1.505(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform (Sparingly), DMSO (Slightly) | [form ]
neat | [pka]
8.17±0.30(Predicted) | [color ]
Colourless oily liquid. | [Odor]
at 100.00 %. fresh herbal orchid green | [Odor Type]
herbal | [Water Solubility ]
0.28g/L(37 ºC) | [BRN ]
2453103 | [LogP]
5.5 at 30℃ | [CAS DataBase Reference]
6259-76-3(CAS DataBase Reference) | [NIST Chemistry Reference]
N-hexyl salicylate(6259-76-3) | [EPA Substance Registry System]
6259-76-3(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
UN 3082 9 / PGIII | [WGK Germany ]
2
| [RTECS ]
DH2207000
| [Toxicity]
Both the acute oral LD50 value in rats and the acute dermal LD50 value in rabbits exceeded 5 g/kg (Moreno, 1975). |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless and transparent oil liquid | [Chemical Properties]
Hexyl Salicylate has been reported in carnation flower absolute
. It is a colorless liquid with a green, floral, spicy odor, reminiscent of azaleas.
It is used for blossom and herbal notes in perfumes, for example, in soaps,
personal hygiene products, and detergents. | [Occurrence]
Has apparently not been reported to occur in nature. | [Uses]
Hexyl salicylate may be used as an internal standard for the determination of allergenic ester, benzyl salicylate in propolis specimens using gas chromatography-mass spectrometry (GC?MS), high-performance liquid chromatography (HPLC), and ultraviolet-visible (UV?Vis) spectrophotometry. It may also be used as a standard fragrance material for the quantification of the analyte in wastewater treatment plants using gas chromatography-mass spectrometry (GC?MS). | [Definition]
ChEBI: Hexyl salicylic acid is a benzoate ester. | [Preparation]
By methyl salicylate exchange with n-hexanol using a sodium methoxylate catalyst. | [General Description]
Hexyl salicylate belongs to the class of flavor & fragrance standards, for use in food, beverage and cosmetic industry. These standards are widely used to add taste and/or smell to products without aroma, to mask unpleasant odors and to maintain stability of original flavor. | [Flammability and Explosibility]
Nonflammable | [Metabolism]
Because of the widespread medicinal use of salicyclic acid and its derivatives, there is an extensive literature on the metabolism and excretion of these compounds. Most esters of salicyclic acid hydrolyse to salicylic acid in the body, but this occurs more readily with the lower esters, little of the amyl ester being split. A large proportion of salicylic acid is excreted unchanged by most species; salicyluric acid, gentisic acid, and salicylglucuronides are also known to be excreted (Williams. 1959). Salicylic acid has been found to be teratogenic to rats (Koshakji. 1972). |
|
|