Identification | More | [Name]
N-(HYDROXYMETHYL)ACETAMIDE | [CAS]
625-51-4 | [Synonyms]
ACETAMIDOMETHANOL HYDROXYMETHYLACETAMIDE(N-) N-ACETYLMETHANOLAMINE N-(HYDROXYMETHYL)ACETAMIDE n-(hydroxymethyl)-acetamid N-(Hydroxymethyl)acetamide,98+% Hydroxymethylacetamide | [EINECS(EC#)]
210-897-2 | [Molecular Formula]
C3H7NO2 | [MDL Number]
MFCD00014417 | [Molecular Weight]
89.09 | [MOL File]
625-51-4.mol |
Chemical Properties | Back Directory | [Appearance]
white to light yellow crystalline powder | [Melting point ]
48-52 °C | [Boiling point ]
165.17°C (rough estimate) | [density ]
1.14
| [refractive index ]
1.4368 (estimate) | [storage temp. ]
Store at 0°C | [form ]
Crystalline | [pka]
13.28±0.10(Predicted) | [Water Solubility ]
Soluble | [Sensitive ]
Hygroscopic | [Merck ]
14,4242 | [BRN ]
506226 | [InChIKey]
HWJHZLJIIWOTGZ-UHFFFAOYSA-N | [CAS DataBase Reference]
625-51-4(CAS DataBase Reference) |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust . S24/25:Avoid contact with skin and eyes . S36:Wear suitable protective clothing . S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [RTECS ]
AC3610000
| [F ]
10 | [HazardClass ]
IRRITANT |
Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystalline powder | [Uses]
Antiseptic, disinfectant especially for surgical instruments. | [Uses]
N-(Hydroxymethyl)acetamide (cas# 625-51-4) is used as a catalyst in the method for manufacturing sol-gel silica particles method for manufacturing coating substrate coated with silica particles. | [Purification Methods]
Recrystallise it from freshly distilled Me2CO, wash the crystals with dry Et2O and dry them in a vacuum desiccator over P2O5. RF 0.4 on paper chromatography with CHCl3/EtOH (2:8) as solvent and developed with ammoniacal AgNO3. It also crystallises in needles from EtOAc containing a few drops of Me2CO. It is hygroscopic and should be stored under dry conditions. [Bachmann et al. J Am Chem Soc 73 2775 1951, Walter et al. Chem Ber 99 3204 1966, Einhorn & Ladisch Justus Liebigs Ann Chem 343 265 1905, Beilstein 2 IV 405.] |
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