Identification | More | [Name]
L-XYLOSE | [CAS]
609-06-3 | [Synonyms]
L-XYL L-(-)-XYLOSE L-XYLOSE XYLOSE XYLOSE, L L-(-)-Xylose, 99+%, mixture of anomers L(-)XYLOSE 99% L-Xylose (9CI) L-Xylose,99% l-(-)-xylose, mixture of anomers XYLOSE, L-(RG) | [EINECS(EC#)]
210-174-1 | [Molecular Formula]
C5H10O5 | [MDL Number]
MFCD00151096 | [Molecular Weight]
150.13 | [MOL File]
609-06-3.mol |
Chemical Properties | Back Directory | [Appearance]
WHITE FINE CRYSTALLINE POWDER | [Melting point ]
150-152 °C(lit.)
| [Boiling point ]
191.65°C (rough estimate) | [density ]
1.525 | [refractive index ]
-20 ° (C=10, H2O) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
H2O: 0.1 g/mL, clear, colorless
| [form ]
Crystalline Powder | [pka]
12.46±0.20(Predicted) | [color ]
White to off-white | [optical activity]
[α]24/D 18.7°, c = 4 in H2O | [Water Solubility ]
within almost transparency | [Sensitive ]
Hygroscopic | [BRN ]
1723080 | [InChIKey]
SRBFZHDQGSBBOR-VVZXFQNISA-N | [LogP]
-2.390 (est) | [CAS DataBase Reference]
609-06-3(CAS DataBase Reference) | [EPA Substance Registry System]
L-Xylose (609-06-3) |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . S36:Wear suitable protective clothing . S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [F ]
3-10 | [TSCA ]
Yes | [HS Code ]
29400090 |
Hazard Information | Back Directory | [Chemical Properties]
WHITE FINE CRYSTALLINE POWDER | [Uses]
L-Xylose is used in the synthesis of L-Xylose derivatives as selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes. | [Application]
l-Xylose is a suitable starting material for the production of L-ribonucleosides. L- Xylose can be converted into an L-ribose derivative via oxidation and reduction steps. This product is then glycosylated to give L-ribonucleosides: L-uridine, L-cytidine, L- adenosine and L-guanosine (Moyroud and Strazewski, 1999; Chelain et al., 1995). L-Xylose can also be used as a starting material for the production of polyhydroxypyrrolidines and related analogues. These compounds have many biological activities. They are shown to have anti-HIV effects, inhibit tumor growth, and also act as ?- and ?-glucosidase inhibitors, which is of relevance for the development of diabetes drugs (Behr and Guillerm, 2007). | [Definition]
ChEBI: A xylose of ring-opened form having L-configuration. | [Preparation]
L-Xylose can be produced from L-xylulose by isomerization. This can be achieved either enzymatically or chemically under alkaline conditions. The equilibrium of the reaction between D-xylose and D-xylulose in an aqueous solution has been determined at pH 6.8-7.4 and at 25 °C to be 85:15 in favor of D-xylose (Tewari et al., 1985). |
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