| Identification | More | [Name]
2-Phenoxyethylbromide | [CAS]
589-10-6 | [Synonyms]
1-(2-BROMOETHOXY)BENZENE
1-BROMO-2-PHENOXYETHANE
(2-BROMETHOXY)BENZENE
(2-BROMOETHOXY)BENZENE
2-BROMOETHYL PHENYL ETHER
2-PHENOXYETHYL BROMIDE
AKOS BBS-00006631
AKOS BC-2647
B-BROMOETHYL PHENYL ETHER
B-BROMOPHENETOLE
BETA-BROMOPHENETOL
BETA-BROMOPHENETOLE
BETA-BROMOPHENYLETHYL ETHER
BETA-PHENOXYETHYL BROMIDE
B-PHENOXYETHYL BROMIDE
PHENOXYETHYLBROMIDE
(2-bromoethoxy)-benzen
Benzene,(2-bromoethoxy)-
-Bromophenetole
Phenetole, beta-bromo- | [EINECS(EC#)]
209-634-4 | [Molecular Formula]
C8H9BrO | [MDL Number]
MFCD00000234 | [Molecular Weight]
201.06 | [MOL File]
589-10-6.mol |
| Chemical Properties | Back Directory | [Appearance]
White Solid | [Melting point ]
31-34 °C(lit.) | [Boiling point ]
144 °C40 mm Hg(lit.) | [density ]
1.45 | [refractive index ]
1.555-1.557
| [Fp ]
150 °F
| [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
Solubility in methanol is almost transparent. Soluble in chloroform and ethyl acetate. | [form ]
Liquid After Melting | [color ]
Clear colorless | [Water Solubility ]
Insoluble in water. Solubility in methanol is almost transparent. Soluble in chloroform and ethyl acetate. | [BRN ]
508290 | [CAS DataBase Reference]
589-10-6(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzene, (2-bromoethoxy)-(589-10-6) | [EPA Substance Registry System]
589-10-6(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S24/25:Avoid contact with skin and eyes . | [RIDADR ]
1325 | [WGK Germany ]
3 | [Hazard Note ]
Irritant | [TSCA ]
Yes | [HazardClass ]
4.1 | [PackingGroup ]
II | [HS Code ]
29093038 |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
It is used in the synthesis and antihypertensive activity of 4'-substituted spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-ones. | [Application]
2-Phenoxyethyl bromide can be used as a pharmaceutical intermediate for the synthesis of nafazodone and oxiperomide. | [Preparation]
2-Phenoxyethyl bromide is synthesized by the reaction of phenol and dibromoethane. Put phenol, dibromoethane and sodium hydroxide in a reaction pot and stir and mix, react at 110 °C for 6 hours, recover dibromoethane, the recovery amount is about 60%, wash with 5% sodium hydroxide solution and water, and divide Take the oil layer, distill under reduced pressure, and collect the fractions at 130-150°C (6.7kPa) to obtain (2-bromoethoxy)benzene. |
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