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ChemicalBook--->CAS DataBase List--->564476-32-0

564476-32-0

564476-32-0 Structure

564476-32-0 Structure
IdentificationBack Directory
[Name]

Bromo-PEG4-t-butyl ester
[CAS]

564476-32-0
[Synonyms]

564476-32-0
Br-PEG4-COOtBu
Br-PEG4-C2-Boc
CAS_564476-32-0
Br-PEG4-CH2CH2COOtBu
Br-PEG4-t-butyl ester
Bromo-PEG4-t-butyl ester
Bromo-PEG5-t-butyl ester
4,7,10,13-Tetraoxapentadecanoic acid, 15-bromo-, 1,1-dimethylethyl ester
3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-bromo-, 1,1-dimethylethylester
[Molecular Formula]

C15H29BrO6
[MDL Number]

MFCD22574808
[MOL File]

564476-32-0.mol
[Molecular Weight]

385.29
Chemical PropertiesBack Directory
[Boiling point ]

415.8±35.0 °C(Predicted)
[density ]

1.210±0.06 g/cm3(Predicted)
[solubility ]

Soluble in DMSO, DCM, DMF
[form ]

Liquid
[color ]

Colorless to light yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Description]

Bromo-PEG4-t-butyl ester is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
[Biological Activity]

Br-PEG4-C2-Boc is a cleavable ADC linker containing 4 units of PEG, which can be used to synthesize antibody drug conjugates (ADC).
[target]

Cleavable

PEGs

Alkyl/ether

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