| Identification | More | [Name]
Basic Red 5 | [CAS]
553-24-2 | [Synonyms]
2,8-Phenazinediamine,N8,N8-3-trimethyl-,monohydrochloride
3-amino-7-(dimethylamino)-2-methyl-phenazinhydrochloride
3-amino-7-(dimethylamino)-2-methyl-phenazinmonohydrochloride
8-phenazinediamine,n8,n8,3-trimethyl-monohydrochloride
aminodimethylaminotoluaminozinehydrochloride
c.i.basicred5
c.i.basicred5,monohydrochloride
cervenneutralni
cerventoluylenova
cervenzasadita5
michromeno.226
n(sup8),n(sup8),3-trimethyl-2,8-phenazinediaminemonohydrochloride
neutralredchloride
neutralredw
N8,N8,3-trimethyl-2,8-phenazinediamine monohydrochloride
NEUTRAL RED SOLUTION
NEUTRAL RED PURIFIED
NEUTRAL RED, FOR MICROSCOPY
NEUTRAL RED CERTIFIED (C.I. 50040)
NEUTRAL RED CELL CULTURE TESTED | [EINECS(EC#)]
209-035-8 | [Molecular Formula]
C15H17ClN4 | [MDL Number]
MFCD04119237 | [Molecular Weight]
288.775 | [MOL File]
553-24-2.mol |
| Chemical Properties | Back Directory | [Appearance]
dark green powder | [Melting point ]
290 °C (dec.) (lit.) | [Boiling point ]
441.31°C (rough estimate) | [density ]
1.1590 (rough estimate) | [refractive index ]
1.6110 (estimate) | [storage temp. ]
Store at 0-5°C | [solubility ]
H2O: soluble10mg/mL | [Colour Index ]
50040 | [form ]
Solid | [pka]
6.7, 7.4(at 25℃) | [color ]
Very dark green | [Odor]
Odorless | [PH]
3.1 (10g/l, H2O, 20℃) | [PH Range]
6.8(red)-8(yellow) | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [Water Solubility ]
50 g/L | [λmax]
540nm, 533nm, 544nm, 529nm, 454nm | [Merck ]
6488 | [BRN ]
3918740 | [Biological Applications]
Detecting pathogens,bacterial infections; treating age-related macular degeneration,burns,cancer,diabetes,obesity,fungal infections,viral diseases | [Major Application]
Fuel cell power generation system, liquid crystal displays, solor cells, sensors, thermochromic materials, coloring wood, detergents, assessment of tobacco smoke, cosmetics, detect bacterial infections, multidrug resistance inhibitors, treatment of burns, endodontic, diabetes, obesity, cancer, age-related macular degeneration, viral diseases | [CAS DataBase Reference]
553-24-2(CAS DataBase Reference) | [EPA Substance Registry System]
553-24-2(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R68:Possible risk of irreversible effects.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S36/37:Wear suitable protective clothing and gloves .
S37/39:Wear suitable gloves and eye/face protection .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [RTECS ]
SG1400000
| [TSCA ]
Yes | [HS Code ]
32041300 | [Toxicity]
LD50 intraperitoneal in mouse: 432mg/kg |
| Hazard Information | Back Directory | [Chemical Properties]
dark green powder | [Uses]
Neutral Red is used as indicator for nitrogen determination; pH indicator.
| [Application]
Transition of pH Indicator: pH 6.8 - 8.0, red to yellow. Basic red 5 is a dye used in histology for staining nuclei. It is also a pH indicator. As such it is used in microbial culture media for differentation of bacteria. For example MacConkey agar contains it and lactose. Acidification by lactic acid turns on the Basic red 5. Therefore, colonies formed by bacteria that ferment lactose into lactic acid will turn red and stand out from the pale colonies of non-lactose-fermenting bacteria. Basic red 5 is also used in cell viability tests based on the ability to incorporate and bind it. | [Definition]
ChEBI: A hydrochloride obtained by combining the free base of neutral red with one equivalent of hydrochloric acid. Neutral red acts as a pH indicator, changing from red to yellow between pH 6.8 and 8.0. | [Preparation]
(a) N,N-dimethyl-4-nitrosobenzenamine?and 4-Methylbenzene-1,3-diamine???reaction, form Toluylene Blue (Basic Dye, C.I. 49410), heating make cyclization; (b) oxidation N1,N1-dimethylbenzene-1,4-diamine?, and 4-Methylbenzene-1,3-diamine mixture. | [General Description]
Neutral red (C.I. 50040) is a protonated diaminophenazine dye. It is aminodimethylaminomethylphenazinehydrochloride, C15H17N4Cl. | [Biochem/physiol Actions]
Neutral red is a widely used cationic fluorochrome that is known to accumulate in the Golgi complex and nuclei after first staining lysosomes. | [Biotechnological Applications]
Neutral Red is a non-toxic stain used for studies of living cells, for example to observe plasmolysis. The stain is used as an aqueous solution (0.1 %, w/v) and stains lipids in vacuoles and certain cell walls. | [storage]
+4°C | [Staining Procedures]
Neutral Red is a non-toxic stain used for studies of living cells, for example to observe plasmolysis. The stain is used as an aqueous solution (0.1 %, w/v) and stains lipids in vacuoles and certain cell walls. | [Properties and Applications]
red light purple and red. Soluble in water is cherry red, soluble in ethanol for product red colour with red fluorescent light brown. The strong sulfuric acid for green, blue for diluted, and then into a product red. The dye solution to join strong sodium hydroxide solution have yellow brown precipitation. | [Purification Methods]
In aqueous solution it is red at pH 6.8 and yellow at pH 8.0. [Beilstein 25 III/IV 3054.] |
|
|