| Identification | Back Directory | [Name]
LIQUIRITIN(SH) | [CAS]
551-15-5 | [Synonyms]
Likviritin
Liquiritin
Liquiritoside
LIQUIRITIN(SH)
Liquiritin(Liquiritoside)
7-Hydroxyflavanone 4'-O-glucoside
4',7-Dihydroxyflavanone4'-(β-D-glucopyranoside)
(2S)-2α-[4-(β-D-Glucopyranosyloxy)phenyl]-7-hydroxychroman-4-one
2,3-Dihydro-7-hydroxy-2-[4-(β-D-glucopyranosyloxy)phenyl]-4H-1-benzopyran-4-one
(S)-2,3-Dihydro-7-hydroxy-2-[4-(β-D-glucopyranosyloxy)phenyl]-4H-1-benzopyran-4-one
(S)-2-[4-(β-D-Glucopyranosyloxy)phenyl]-2,3-dihydro-7-hydroxy-4H-1-benzopyran-4-one
(2S)-2,3-Dihydro-7-hydroxy-2-[4-(β-D-glucopyranosyloxy)phenyl]-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one,2-[4-(b-D-glucopyranosyloxy)phenyl]-2,3-dihydro-7-hydroxy-,(2S)-
(S)-7-Hydroxy-2-[4-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyltetrahydropyran-2-yloxy)phenyl]chroman-4-one | [EINECS(EC#)]
607-884-2 | [Molecular Formula]
C21H22O9 | [MDL Number]
MFCD00210526 | [MOL File]
551-15-5.mol | [Molecular Weight]
418.396 |
| Chemical Properties | Back Directory | [Melting point ]
208 °C(Solv: ethanol (64-17-5)) | [Boiling point ]
746.8±60.0 °C(Predicted) | [density ]
1.529±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
7.70±0.40(Predicted) | [color ]
White to Off-White | [biological source]
Glycyrrhizae root (licorice root) | [Stability:]
Light Sensitive | [InChIKey]
DEMKZLAVQYISIA-ZRWXNEIDSA-N |
| Hazard Information | Back Directory | [Uses]
Liquiritin is a major constituent of Glycyrrhiza Radix that has a neuroprotective effect against glutamate toxicity in DPC12 cells and may have potential for the treatment of neurodegenerative diseases. | [Definition]
ChEBI: A flavanone glycoside that is liquiritigenin attached to a beta-D-glucopyranosyl residue at position 4' via a glycosidic linkage. | [Biological Activity]
Liquiritin has been attributed to show antidepressant-like and antioxidant activity. It causes apoptosis in cell lines having gastric cancer and promyelocytic leukemia. Liquiritin also demonstrates neurotrophic effects and hence has been considered as a potential contender for the management of different neurodegenerative diseases. It shows an anti-inflammatory property with protection to the liver against oxidative damage. It has depigmenting ability and is a potential medicine for melasma. | [storage]
Store at 2-8°C, protect from light |
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