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ChemicalBook--->CAS DataBase List--->55-43-6

55-43-6

55-43-6 Structure

55-43-6 Structure
IdentificationMore
[Name]

N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE
[CAS]

55-43-6
[Synonyms]

DIBENAMINE HYDROCHLORIDE
N-(2-CHLOROETHYL)DIBENZYLAMINE HCL
N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE
N,N'-DIBENZYL-2-CHLOROETHYLAMINE HYDROCHLORIDE
N,N-DIBENZYL-2-CHLOROETHYLAMINE HYDROCHLORIDE
N,N-DIBENZYLAMINOETHYLCHLORIDE HYDROCHLORIDE
N,N-DIBENZYL-BETA-CHLOROETHYLAMINE HYDROCHLORIDE
dibenzylchlorethylaminehydrochloride
n-(2-chloroethyl)-dibenzylaminhydrochloride
n-(2-chloroethyl)-n-(phenylmethyl)-benzenemethanaminhydrochloride
dibenzyl(2-chloroethyl)ammonium chloride
n,n-dibenzyl-2-chloroethylamineHCl
DIBENZYLAMINE,N-(2-CHLOROETHYL)-,HYDROCHLORIDE
N-(2-Chloroethyl)-N-(phenylmethyl)benzmetanamine chlorohydrate
Sympatholytin hydrochloride
[EINECS(EC#)]

200-234-5
[Molecular Formula]

C16H19Cl2N
[MDL Number]

MFCD00012518
[Molecular Weight]

296.23
[MOL File]

55-43-6.mol
Chemical PropertiesBack Directory
[Melting point ]

190-193 °C(lit.)
[Boiling point ]

449.72°C (rough estimate)
[density ]

1.1507 (rough estimate)
[refractive index ]

1.6300 (estimate)
[storage temp. ]

Inert atmosphere,Room Temperature
[solubility ]

almost transparency in Methanol
[form ]

Crystalline Powder
[color ]

White to off-white
[Merck ]

2138
[CAS DataBase Reference]

55-43-6(CAS DataBase Reference)
[EPA Substance Registry System]

N-(2-Chloroethyl)dibenzylamine hydrochloride (55-43-6)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
[WGK Germany ]

3
[RTECS ]

HQ6825000
[HazardClass ]

IRRITANT
[HS Code ]

29214900
[Toxicity]

LD50 s.c. in mice: 800 mg/kg (Nickerson, Nomaguchi)
Hazard InformationBack Directory
[Uses]

Sympatholytin was used as 5-Hydroxytryptamine antagonists in this study.Sympatholytin preferentially blocked postsynaptic alpha receptors.
[General Description]

N-(2-Chloroethyl)dibenzylamine hydrochloride is also referred as dibenamine. Mechanism of protection against carbon tetrachloride-induced hepatotoxicity produced by pretreatment with [N-(2-chloroethyl) dibenzylamine] hydrochloride has been investigated. It is a powerful adrenergic blocking agent, is known to modify the pharmacological effects of epinephrine.
[in vivo]

Dibenamine hydrochloride (subcutaneous?injection; 25 mg/kg; 48 and 24 hr before the administration of CCl4) decreases the CHCl3, levels at 2 and 6 hr by 30-50 percent, but did not appreciably affect the half-life of CHCl3, in the liver.Pretreatment with Dibenamine apparently slows the conversion of Ccl4 to CHCL3[1].

Spectrum DetailBack Directory
[Spectrum Detail]

N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE(55-43-6)MS
N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE(55-43-6)1HNMR
N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE(55-43-6)13CNMR
N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE(55-43-6)IR1
N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE(55-43-6)IR2
N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE(55-43-6)IR3
N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE(55-43-6)Raman
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

55-43-6(sigmaaldrich)
[TCI AMERICA]

N-(2-Chloroethyl)dibenzylamine Hydrochloride,>98.0%(N)(55-43-6)
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