| Identification | Back Directory | [Name]
methyl protodioscin | [CAS]
54522-52-0 | [Synonyms]
NSC-698790
Smilax saponin B
methyl protodioscin
22-Methoxylprotodioscin
22-O-Methylprotodioscin
Methyl protodioscin, BR
Methylprotodioscin 54522-52-0
Methyl protodioscin (NSC-698790
Methylprotodioscin(SMilax saponin B)
3b,26-Dihydroxy-22a-methoxyfurost-5-ene 3-O-beta-chacotrioside 26-O-beta-D-glucopyranoside
[(25R)-26-(β-D-Glucopyranosyloxy)-22α-methoxyfurost-5-en-3β-yl]2-O,4-O-bis(α-L-rhamnopyranosyl)-β-D-glucopyranoside
[(22R,25R)-22-Methoxy-26-(β-D-glucopyranosyloxy)furosta-5-ene-3β-yl]2-O,4-O-di-α-L-rhamnopyranosyl-β-D-glucopyranoside
β-D-Glucopyranoside, (3β,22α,25R)-26-(β-D-glucopyranosyloxy)-22-methoxyfurost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]- | [Molecular Formula]
C52H86O22 | [MDL Number]
MFCD30478892 | [MOL File]
54522-52-0.mol | [Molecular Weight]
1063.23 |
| Chemical Properties | Back Directory | [Melting point ]
175-177 °C | [density ]
1.43 | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Methanol (Slightly), Pyridine (Slightly), Water (Slightly) | [form ]
Solid | [pka]
12?+-.0.70(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
Methylprotodioscin is a steroidal saponin compound found in a number of plant species. It is known to be the active component of the herbal aphrodisiac plant Tribulus terrestris. It has also shown to produce significant increases in the levels of the hormonal levels in animal studies. | [Definition]
ChEBI: Methylprotodioscin is a steroid saponin. | [Biological Activity]
Methyl protodioscin is a saponin isolated from medical plant Dioscoreaceae th at exhibit anticancer properties. It appears th at Methyl protodioscin inhibits proliferation and promoted apoptosis of pancreatic cancer through suppression of glycolysis. Methyl protodioscin protects r at brain from I/R injury through down-regulation Mul1 (Mitochondrial E3 ubiquitin ligase 1) and elevation of SOD2 (superoxide dismutase 2) protein levels. |
|
|