| Identification | More | [Name]
Cynaroside | [CAS]
5373-11-5 | [Synonyms]
CYNAROSIDE
LUTEOLIN-7-GLUCOSIDE
LUTEOLIN-7-O-GLUCOSIDE
PETUNIDIN
2-(3,4-dihydroxyphenyl)-7-(beta-d-glucopyranosyloxy)-5-hydroxy-4h-1-benzopyr
4h-1-benzopyran-4-one,2-(3,4-dihydroxyphenyl)-7-(beta-d-glucopyranosyloxy)-5-h
7-glucoluteolin
7-glucosylluteolin
cinaroside
glucoluteolin
luteolin7-monoglucoside
luteolin7-o-glucopyranoside
luteoloside
LUTEOLIN-7-O-GLUCOSIDE 98+%
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(.beta.-D-glucopyranosyloxy)-5-hydroxy-
Galuteolin
LUTEOLIN-7-GLUCOSIDE hplc
2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
Luteolin 7-O-D-glucoside
LUTEOLIN-7-O-GLUCOSIDE WITH HPLC | [EINECS(EC#)]
226-365-8 | [Molecular Formula]
C21H20O11 | [MDL Number]
MFCD06799436 | [Molecular Weight]
448.38 | [MOL File]
5373-11-5.mol |
| Chemical Properties | Back Directory | [Melting point ]
256～258℃ | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [Boiling point ]
838.1±65.0 °C(Predicted) | [density ]
1.713±0.06 g/cm3(Predicted) | [form ]
neat | [pka]
6.10±0.40(Predicted) | [color ]
Yellow to Very Dark Yellow | [Stability:]
Hygroscopic | [InChIKey]
PEFNSGRTCBGNAN-QNDFHXLGSA-N | [SMILES]
C1(C2=CC=C(O)C(O)=C2)OC2=C(C(O)=CC(O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)=C2)C(=O)C=1 |&1:17,18,20,22,24,r| | [LogP]
-0.090 (est) | [CAS DataBase Reference]
5373-11-5(CAS DataBase Reference) |
| Questions And Answer | Back Directory | [Effects]
Luteolin has a strong bactericidal effect on the respiratory tract, and it is the main active ingredient in the treatment of bronchitis in Qinglan, a unique medicinal material in Xinjiang. Lowers the role of cholesterol in atherosclerosis and enhances capillary relaxation. |
| Hazard Information | Back Directory | [Description]
Luteoloside is a flavonoid that has been found in many Chinese herbs with diverse biological activities.1,2,3,4 It reduces lactate dehydrogenase (LDH) and caspase-3 activities and production of reactive oxygen species (ROS) and increases cell viability and 14-3-3η protein levels in H9C2 cardiomyocytes after anoxia/reoxygenation injury.1 Luteoloside blocks 3C protease activity (IC50 = 0.36 mM) and reduces the cytopathic effect of enterovirus 71 in rhabdomyosarcoma cells (EC50 = 0.43 mM).2 It inhibits the growth of hepatocellular carcinoma (HCC) cells in vitro via reduction in ROS accumulation, caspase-1 activity, and expression of the NLRP3 inflammasome and reduces the number of lung metastases in an SMMC-7721 HCC mouse xenograft model when administered at a dose of 2 mg/kg.3 Luteoloside also reduces acanthosis and expression of epidermal differentiation markers in a mouse model of psoriasis induced by imiquimod (Item No. 14956).4 | [Chemical Properties]
Off-white powder | [Uses]
Luteolin 7-Glucoside is a strong antioxidant ant radical scavenger. Used in cancer prevention. | [Definition]
ChEBI: A glycosyloxyflavone that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. |
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