Identification | More | [Name]
N-Acetyl-L-tyrosine | [CAS]
537-55-3 | [Synonyms]
ACETYL-L-TYROSINE ACETYLTYROSINE AC-TYR-OH AC-TYROSINE L-TYROSINE, N-ACETYL- N-ACETYL-L-TYROSINE N-ACEYL-L-TYROSINE N-AC-L-TYR N-ALPHA-ACETYL-L-TYROSINE n-acetyl-l-tyrosin N-Acetyltyrosine Tyrosine, N-acetyl-, L- N-Ac-Tyr N-Acetyl-L-Tyrosine AJI92 2-acetylamino-3-(4-hydroxyphenyl)-propanoic acid N-ACETYL-L-TYROSINE N-ACETYL-L-TYROSINE extrapure for biochemistry N-Acetyl-L-tyrosine ,98% | [EINECS(EC#)]
208-671-3 | [Molecular Formula]
C11H13NO4 | [MDL Number]
MFCD00037190 | [Molecular Weight]
223.23 | [MOL File]
537-55-3.mol |
Chemical Properties | Back Directory | [Appearance]
solid | [Melting point ]
149-152 °C(lit.)
| [alpha ]
47.5 º (c=2, water) | [Boiling point ]
364.51°C (rough estimate) | [density ]
1.2446 (rough estimate) | [refractive index ]
1.4960 (estimate) | [storage temp. ]
2-8°C
| [solubility ]
H2O: soluble25mg/mL | [form ]
Crystalline | [pka]
3.15±0.10(Predicted) | [color ]
White to Off-White | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [Water Solubility ]
Soluble in water (25 mg/ml), and ethanol. | [Detection Methods]
T,NMR,Rotation | [BRN ]
2697172 | [LogP]
1.320 | [CAS DataBase Reference]
537-55-3(CAS DataBase Reference) | [NIST Chemistry Reference]
N-acetyl-Tyr(537-55-3) | [EPA Substance Registry System]
537-55-3(EPA Substance) |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R41:Risk of serious damage to eyes. R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S39:Wear eye/face protection . S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [F ]
10 | [TSCA ]
Yes | [HS Code ]
29242990 |
Hazard Information | Back Directory | [Chemical Properties]
N-Acetyl-L-Tyrosine is a white crystalline powder that is an acetyl derivative of the amino acid, L-tyrosine. It is freely soluble in water compared to L-tyrosine and is commonly used as a parenteral nutrition supplement. N-Acetyl-L-tyrosine , a stable and more soluble form of tyrosine , has been incorporated in some currently available commercial parenteral amino acid formulations such as TrophAmine and Aminosyn-II. | [Uses]
N-Acetyl-L-tyrosine is involved in catecholamine production. It can be used as a cell culture media component in the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. | [Application]
N-Acetyl-L-tyrosine is a tyrosine derivative with a chemical structure similar to that of an amino acid. It is used as a model system in biochemistry and molecular biology to study the transfer reactions of tyrosine, which are important for energy metabolism, protein synthesis, and metal chelation. N-acetyl-L-tyrosine may be used as an indicator to distinguish neurosyphilis patients from syphilis/non-neurosyphilis patients. N-acetyl-L-tyrosine is a precursor of the essential neurotransmitter dopamine. | [Definition]
ChEBI: N-acetyl-L-tyrosine is an N-acetyltyrosine in which the chiral centre has L configuration. It has a role as an EC 2.1.1.4 (acetylserotonin O-methyltransferase) inhibitor, a biomarker and a human urinary metabolite. It is a N-acyl-L-tyrosine and a N-acetyltyrosine. It is a conjugate acid of a N-acetyl-L-tyrosinate. | [benefits]
N-Acetyl-L-Tyrosine (NALT) plays a necessary part in the synthesis of dopamine and other hormones in your body. It can boost levels of the neurotransmitters dopamine, norepinephrine and epinephrine. It helps to support higher levels of focus and cognitive function. It can increase working memory and feelings of well-being. | [Side effects]
L-tyrosine gets the generally regarded as safe (GRAS) stamp of approval from the FDA. Some side effects of N-Acetyl-L-tyrosine (NALT) include nausea, headache, fatigue, and heartburn. It can be safely taken for extended periods of time. |
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