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ChemicalBook--->CAS DataBase List--->5302-45-4

5302-45-4

5302-45-4 Structure

5302-45-4 Structure
IdentificationBack Directory
[Name]

3-N-OXALYL-L-2,3-DIAMINOPROPANOICACID
[CAS]

5302-45-4
[Synonyms]

ODAP
BOAA
β-ODAP
10-25Mg
β-L-ODAP
Dencichin
L-Dencichin
beta-ODAP >=98% (HPLC)
β-N-Oxalylamino-L-alanine
BETA-N-OXALAMINO-L-ALANINE
BETA-N-OXYALYLAMINE-L-ALANINE
DENCICHINE; L-DENCICHIN; ODAP
N3-oxalyl-L-2,3-diaminopropionicaci
3-[(Carboxycarbonyl)amino]-L-alanine
3-N-OXALYL-L-2,3-DIAMINOPROPANOICACID
L-Alanine, 3-[(carboxycarbonyl)amino]-
N(3)-oxalyl-L-2,3-diaminopropionic acid
BETA-N-OXALYL-ALPHA,BETA-DIAMINOPROPIONICACID
(S)-2-AMino-3-(carboxyforMaMido)propanoic acid
(S)-2-Amino-3-[(1,2-dioxo-2-hydroxyethyl)amino]propionic acid
[Molecular Formula]

C5H8N2O5
[MDL Number]

MFCD00055228
[MOL File]

5302-45-4.mol
[Molecular Weight]

176.13
Chemical PropertiesBack Directory
[density ]

1.596±0.06 g/cm3 (20 ºC 760 Torr)
[storage temp. ]

Keep in dark place,Sealed in dry,2-8°C
[solubility ]

0.1 M HCl: soluble2mg/mL, clear (warmed)
[form ]

powder
[pka]

1.99±0.10(Predicted)
[color ]

white to beige
[optical activity]

[α]/D -17 to -23°, c = 0.5 (Solvent: 4N HCl)
Hazard InformationBack Directory
[Definition]

ChEBI: An Nbeta-acyl-L-2,3-diaminopropionic acid in which the acyl group is oxalyl.
[Biological Activity]

β-ODAP is a potent inhibitor of HIF-prolyl hydroxylase-2 (PHD-2) th at induces HIF dependent HRE (hypoxia response element) in normoxic conditions. β-ODAP is an analog of glutamic acid present in Lathyrus sativus (grass pea) th at activates AMPA receptors. β-ODAP causes neurolathyrism upon prolonged consumption of L. sativus seeds.''β-ODAP is considered more neurotoxic than α-ODAPthus during food processingits conversion to α isomer is essential. β-ODAP exhibits its neurotoxicity via the activation of metabotropic glutamatergic receptor.
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