| Identification | More | [Name]
19-HYDROXY-4-ANDROSTENE-3,17-DIONE | [CAS]
510-64-5 | [Synonyms]
19-HYDROXY-4-ANDROSTEN-3,17-DIONE
19-HYDROXY-4-ANDROSTENE-3,17-DIONE
19-HYDROXYANDROSTENDIONE
19-HYDROXYANDROSTENEDIONE
4-ANDROSTEN-19-OL-3,17-DIONE
4-ANDROSTENE-3,17-DIONE-19-0L
4-ANDROSTENE-3,17-DIONE-19-OL
Androst-4-ene-3,17-dione, 19-hydroxy-
19-hydroxyandrost-4-ene-3,17-dione
Androst-4-en-19-ol-3,17-dione
Androst-4-ene-3,17-dione-19-ol
NSC 7423
19-HUDROXYANDROST-4-ENE-3,17-DIONE
19-Hydroxyandrost-4-ene-3,17-d
(8S,9S,10S,13S,14S)-10-(hydroxymethyl)-13-methyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione
19-hydroxy-4-androstene-3,17-dione 19-hydroxy-4-androsten-3,17-dione19-Hydroxyandrost-4-ene-3,17-dione
NSC 74233
19-Hydroxy-4-androstene-3,17-dione, 4-Androsten-19-ol-3,17-dione, 4-Androstene-3,17-dione-19-ol
4-Androsten-19-ol-3,17-dione, 4-Androstene-3,17-dione-19-ol | [EINECS(EC#)]
208-116-5 | [Molecular Formula]
C19H26O3 | [MDL Number]
MFCD00003616 | [Molecular Weight]
302.41 | [MOL File]
510-64-5.mol |
| Chemical Properties | Back Directory | [Appearance]
Off-White Solid | [Melting point ]
168-169 °C(lit.) | [Boiling point ]
485.4±45.0 °C(Predicted) | [density ]
1.19±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Store in freezer, under -20°C | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
14.90±0.10(Predicted) | [color ]
Off-White to Pale Yellow | [optical activity]
[α]/D +190±5°, c = 1 in chloroform | [Usage]
A novel substituted estrogen as aromatase inhibitor | [BRN ]
2567249 | [CAS DataBase Reference]
510-64-5(CAS DataBase Reference) | [NIST Chemistry Reference]
19-Hydroxyandrost-4-ene-3,17-dione(510-64-5) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S27:Take off immediately all contaminated clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [HS Code ]
29372900 |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
19-Hydroxyandrostendione is a novel substituted estrogen as aromatase inhibitor. It induces neuroendocrine trans-differentiation of prostate cancer cells via an ectopic olactory receptor. | [Uses]
A novel substituted estrogen as aromatase inhibitor | [Definition]
ChEBI: 19-hydroxyandrost-4-ene-3,17-dione is a 19-hydroxy steroid, a 3-oxo steroid, a 17-oxo steroid and an androstanoid. It has a role as a mouse metabolite. | [Purification Methods]
Recrystallise 19-hydroxy-4-androsten-3,17-dione from Me2CO/hexane or Et2O/hexane. It has UV with max at 242nm in EtOH or MeOH. The 19-acetoxy derivative has [] 26D +185o (CHCl3) and max 237.5nm in EtOH. [Ehrenstein & Dünnenberger J Org Chem 21 774 1956, Beilstein 8 IV2162.] |
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