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ChemicalBook--->CAS DataBase List--->51-66-1

51-66-1

51-66-1 Structure

51-66-1 Structure
IdentificationMore
[Name]

N-(4-Methoxyphenyl)acetamide
[CAS]

51-66-1
[Synonyms]

4-ACETAMIDOANISOLE
4-ACETANISIDIDE
4-ACETANISIDINE
4'-METHOXYACETANILIDE
4-METHOXYACETANILIDE
ACETYL-P-ANISIDINE
AURORA KA-3672
LABOTEST-BB LT00053555
METHACETIN
N-(4-METHOXYPHENYL)ACETAMIDE
N-ACETYL-P-ANISIDINE
P-ACETANISIDIDE
P-ACETANISIDINE
P-METHOXYACETANILIDE
4-(Acetylamino)anisole
4’-methoxy-acetanilid
4-Acetaniside
Acetamide, N-(4-methoxyphenyl)-
Acetamide,N-(4-methoxyphenyl)-
Acetanilide, 4'-methoxy-
[EINECS(EC#)]

200-114-2
[Molecular Formula]

C9H11NO2
[MDL Number]

MFCD00014963
[Molecular Weight]

165.19
[MOL File]

51-66-1.mol
Chemical PropertiesBack Directory
[Appearance]

LIGHT BEIGE CRYSTALLINE POWDER
[Melting point ]

128-130 °C(lit.)
[Boiling point ]

293.03°C (rough estimate)
[density ]

1.1603 (rough estimate)
[refractive index ]

1.5839 (estimate)
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Crystalline
[pka]

14.53±0.70(Predicted)
[color ]

White
[Water Solubility ]

0.42 g/100 mL (20 ºC)
[Merck ]

14,51
[BRN ]

387887
[CAS DataBase Reference]

51-66-1(CAS DataBase Reference)
[NIST Chemistry Reference]

N-(4-Methoxyphenyl)acetic acid amide(51-66-1)
[EPA Substance Registry System]

51-66-1(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

Xn,Xi
[Risk Statements ]

R22:Harmful if swallowed.
R36/38:Irritating to eyes and skin .
[Safety Statements ]

S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
[WGK Germany ]

1
[RTECS ]

AE8290000
[TSCA ]

Yes
[HS Code ]

29242990
[Toxicity]

LD50 orl-mus: 1190 mg/kg TXAPA9 19,20,71
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Acetic acid-->p-Anisidine
[Preparation Products]

Disperse Blue 79-->Azoic Diazo Component 1-->4-METHOXY-2-NITROACETANILIDE-->N-(4-METHOXY-3-NITROPHENYL)ACETAMIDE-->4-Bromo-3-nitroanisole-->3,4-Dimethoxyphenol-->2,6-DICHLORO-1,4-BENZOQUINONE-->TRIPHENYLFLUOROSILANE-->2,5-DIBROMOANISOLE-->Acetaminophen-->Diazo Fast Bordeaux GP
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

N-(4-Methoxyphenyl)acetamide(51-66-1).msds
Hazard InformationBack Directory
[Chemical Properties]

LIGHT BEIGE CRYSTALLINE POWDER
[Uses]

Methacetin is evaluated in a breath test to predict early liver disfunction due to valproic acid and other cause. Methacetin breath test (MBT) is a rapid, non-invasive assessment of liver function in acute severe liver disease and a potential key tool in future dignosis.
[Definition]

ChEBI: Methacetin is a member of the class of acetamides that is paracetamol in which the hydrogen of phenolic hydroxy group has been replaced by a methyl group. It is a member of acetamides and an aromatic ether. It is functionally related to a p-anisidine and a paracetamol.
[Synthesis Reference(s)]

Journal of the American Chemical Society, 89, p. 7131, 1967 DOI: 10.1021/ja01002a061
The Journal of Organic Chemistry, 42, p. 3755, 1977
Organic Syntheses, Coll. Vol. 3, p. 661, 1955
[Safety Profile]

Moderately toxic by ingestion andother unspecified routes. When heated to decomposition itemits toxic fumes of NOx.
Spectrum DetailBack Directory
[Spectrum Detail]

Methacetin(51-66-1)MS
Methacetin(51-66-1)1HNMR
Methacetin(51-66-1)13CNMR
Methacetin(51-66-1)IR1
Methacetin(51-66-1)IR2
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

[Alfa Aesar]

[Sigma Aldrich]

51-66-1(sigmaaldrich)
[TCI AMERICA]

p-Acetanisidide,>98.0%(LC)(T)(51-66-1)
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