| Identification | Back Directory | [Name]
GT 949 | [CAS]
460330-27-2 | [Synonyms]
GT 949
3-((4-Cyclohexylpiperazin-1-yl)(1-phenethyl-1H-tetrazol-5-yl)methyl)-6-methoxyquinolin-2(1H)-one
2(1H)-Quinolinone, 3-[(4-cyclohexyl-1-piperazinyl)[1-(2-phenylethyl)-1H-tetrazol-5-yl]methyl]-6-methoxy- | [Molecular Formula]
C30H37N7O2 | [MDL Number]
MFCD03129031 | [MOL File]
460330-27-2.mol | [Molecular Weight]
527.66 |
| Chemical Properties | Back Directory | [Boiling point ]
770.7±60.0 °C(Predicted) | [density ]
1.32±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 100 mM; Ethanol: 10 mM, heated | [form ]
A solid | [pka]
10.55±0.70(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
GT 949 is a selective EAAT2 positive allosteric modulator (EC50 = 0.26 nM). Enhances the glutamate translocation rate, with no effect on substrate interaction. Increases glutamate removal by 70%. Exhibits no effect on DAT, SERT and NET or NMDA receptors. | [storage]
Store at -20°C |
|
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BOC Sciences
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DC Chemicals
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