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ChemicalBook--->CAS DataBase List--->443-09-4

443-09-4

443-09-4 Structure

443-09-4 Structure
IdentificationMore
[Name]

5'-FLUORO-2'-HYDROXYPROPIOPHENONE
[CAS]

443-09-4
[Synonyms]

1-(5-Fluoro-2-hydroxyphenyl)
2-hydroxy-5-fluoropropiophenone
5'-FLUORO-2'-HYDROXYPROPIOPHENONE
1-(5-FLUORO-2-HYDROXYPHENYL)PROPAN-1-ONE
1-Propanone,1-(5-fluoro-2-hydroxyphenyl)-
JRH-01109, 1-(5-Fluoro-2-hydroxyphenyl)propan-1-one, 97%
[Molecular Formula]

C9H9FO2
[MDL Number]

MFCD00218583
[Molecular Weight]

168.16
[MOL File]

443-09-4.mol
Chemical PropertiesBack Directory
[Melting point ]

35-39 °C
[Boiling point ]

117-121 °C(Press: 22 Torr)
[density ]

1.200±0.06 g/cm3(Predicted)
[Fp ]

219 °F
[pka]

8.26±0.48(Predicted)
[CAS DataBase Reference]

443-09-4(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xn,Xi
[Risk Statements ]

R22:Harmful if swallowed.
R37/38:Irritating to respiratory system and skin .
R41:Risk of serious damage to eyes.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S39:Wear eye/face protection .
[WGK Germany ]

3
[Hazard Note ]

Irritant
Hazard InformationBack Directory
[Preparation]

Preparation by Fries rearrangement of p-fluorophenyl propionate (b.p.18–20 118–120°) with aluminium chloride at 150° for 1 h (80–81%) or at reflux for 30 min (57%)
Also obtained by demethylation of 5-fluoro-2-methoxy-propiophenone (b.p.13 132°) with refluxing pyridinium chloride for 15 min (76%).
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

443-09-4(sigmaaldrich)
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