| Identification | More | [Name]
6-HYDROXYFLAVANONE | [CAS]
4250-77-5 | [Synonyms]
6'-HYDROXYFLAVANONE
6-HYDROXYFLAVANONE
HYDROXYFLAVANONE, 6-
6-Hydroxyflavanone,98+%
HYDROXYFLAVANONE, 6-(RG)
(2R)-6-hydroxy-2-phenyl-chroman-4-one
2-Phenyl-6-hydroxy-3,4-dihydro-2H-1-benzopyran-4-one
6-OH Flavanone | [EINECS(EC#)]
624-472-8 | [Molecular Formula]
C15H12O3 | [MDL Number]
MFCD00017485 | [Molecular Weight]
240.25 | [MOL File]
4250-77-5.mol |
| Chemical Properties | Back Directory | [Appearance]
Slightly yellow-cream powder | [Melting point ]
220-222 °C (dec.) (lit.) | [Boiling point ]
464.3±45.0 °C(Predicted) | [density ]
1.288±0.06 g/cm3(Predicted) | [form ]
powder to crystal | [pka]
9.53±0.40(Predicted) | [color ]
White to Orange to Green | [BRN ]
87354 | [LogP]
2.955 (est) | [CAS DataBase Reference]
4250-77-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [HS Code ]
29329900 |
| Hazard Information | Back Directory | [Chemical Properties]
Slightly yellow-cream powder | [Uses]
6-Hydroxyflavanone (6-HF) has been used for the enantiomeric separation of flavonoids using polysaccharide-based chiral stationary phases by nano-liquid chromatography (nano-LC). Racemic 6-HF may be used in the synthesis of 6-propionoxy-flavanone (6-PF). 6-HF may be employed as synthetic flavone to investigate the mechanism of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induced cytotoxic and apoptotic effects in HeLa cancer cells. | [Definition]
ChEBI: A monohydroxyflavanone that is flavanone substituted by a hydroxy group at position 6. | [General Description]
6-Hydroxyflavanone is a flavonoid. Its biotransformation by Aspergillus niger strains have been described. Crystal structure of S and R enanti-omers of 6-hydroxyflavanone has been reported to have four crystallographic sites of the unit cell in an approximate 3:1/1:3 ratio. It was identified as a metabolite of flavnone on incubation with rat liver microsomes by positive ion electrospray LC/MS analysis. |
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