| Identification | More | [Name]
(-)-Gallocatechin gallate | [CAS]
4233-96-9 | [Synonyms]
[2S,3R]-2-[3,4,5-TRIHYDROXYPHENYL]-3,4-DIHYDRO-1[2H]-BENZOPYRAN-3,5,7-TRIOL 3-[3,4,5-TRIHYDROXYBENZOATE
(-)-GALLOCATECHIN GALLATE
GALLOCATECHIN GALLATE
GALLOCATECHIN GALLATE, (-)-
(-)-GCG
(-)-gallocatecholgallate
(2s-trans)-henyl)-2h-1-benzopyran-3-yleste
benzoicacid,3,4,5-trihydroxy-,3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyp
(−
)-Gallocatechin gallate
(2S,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate)
(-)-gallocatechin gallate from green tea
Gallocatechin gallate (-GCG)
(-)-Gallocatechin gallate
GCG，Gallocatechingallate
(2R)-2,3-Dihydro-2α-(3,4,5-trihydroxyphenyl)-3β-(galloyloxy)-4H-1-benzopyran-5,7-diol
3,4,5-Trihydroxybenzoic acid [[(2R)-3,4-dihydro-5,7-dihydroxy-2α-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran]-3β-yl] ester
(2S)-2-(3,4,5-Trihydroxyphenyl)-3α-(galloyloxy)-5,7-dihydroxychroman
(2S)-3,4-Dihydro-2β-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3α,5,7-triol 3-(3,4,5-trihydroxybenzoate)
(2S,3R)-2-(3,4,5-Trihydroxyphenyl)-3-(3,4,5-trihydroxybenzoyloxy)-3,4-dihydro-2H-1-benzopyran-5,7-diol
3,4,5-Trihydroxybenzoic acid (2S,3R)-2-(3,4,5-trihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-3-yl ester | [EINECS(EC#)]
636-979-1 | [Molecular Formula]
C22H18O11 | [MDL Number]
MFCD00214298 | [Molecular Weight]
458.37 | [MOL File]
4233-96-9.mol |
| Chemical Properties | Back Directory | [Melting point ]
>179oC (dec.) | [Boiling point ]
909.1±65.0 °C(Predicted) | [density ]
1.90±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
neat | [pka]
7.75±0.25(Predicted) | [color ]
Off-White to Pale Brown | [biological source]
green tea | [LogP]
2.080 (est) | [CAS DataBase Reference]
4233-96-9(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
DH9000000
| [HS Code ]
29329990 |
| Hazard Information | Back Directory | [Uses]
(-)-Gallocatechin Gallate is a catechins found in green tea that has shown to suppress the activity of cytochrome P 450 1A1. | [Definition]
ChEBI: (-)-gallocatechin gallate is a gallate ester obtained by formal condensation of the carboxy group of gallic acid with the (3R)-hydroxy group of (-)-gallocatechin. A natural product found in found in green tea. It has a role as an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor, a human xenobiotic metabolite, an antineoplastic agent and a plant metabolite. It is a gallate ester, a polyphenol and a catechin. It is functionally related to a (-)-gallocatechin and a gallic acid. It is an enantiomer of a (+)-gallocatechin gallate. | [Biological Activity]
Tea catechins like (-)-Gallocatechin gallate are known to have antiviralantioxidativeantimutagenic and antiobesity activities. It exhibits human immunodeficiency virus-1 (HIV-1) integrase inhibitory activity by disturbing the interaction between the human immunodeficiency virus-1 (HIV-1) integrase and virus DNA. GCG also shows impeding effect on the release of vero toxins (VTs) by enterohemorrhagic Escherichia coli. It displays an inhibitory effect on cholesterol absorption and is reported to be more effective than tea catechins in lowering plasma cholesterolthus preventing atherosclerosis. |
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