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ChemicalBook--->CAS DataBase List--->420849-22-5

420849-22-5

420849-22-5 Structure

420849-22-5 Structure
IdentificationBack Directory
[Name]

TIQ-A
[CAS]

420849-22-5
[Synonyms]

Thieno[2,3-c]isoquinolin-5(4H)-one
[Molecular Formula]

C11H7NOS
[MDL Number]

MFCD06407947
[MOL File]

420849-22-5.mol
[Molecular Weight]

201.24
Chemical PropertiesBack Directory
[Melting point ]

256-258°C
[Boiling point ]

282.2±9.0 °C(Predicted)
[density ]

1.358±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMSO: 16 mg/mL, soluble
[form ]

solid
[pka]

13.04±0.20(Predicted)
[color ]

Light green to green
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

20/21/22
[WGK Germany ]

3
Hazard InformationBack Directory
[Chemical Properties]

Dark Brown Solid
[Uses]

A cell permeable, potent PARP inhibitor with an IC50 of 450nM. Shown to be neuroprotective against oxygen-glucose deprivation injury in vitro in cultured murine cortical cells ( IC50 of 150nM) and i n vivi in rat transient focal ischemia model (3 mg/kg ip).
[Uses]

A cell permeable, potent PARP inhibitor with an IC50 of 450nM. Shown to be neuroprotective against oxygen-glucose deprivation injury in vitro in cultured murine cortical cells ( IC50 of 150nM) and in vivi in rat transient focal ischemia model (3 mg/kg ip).
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

TIQ-A(420849-22-5)1HNMR
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