| Identification | More | [Name]
3-(4-FLUOROBENZOYL)PROPIONIC ACID | [CAS]
366-77-8 | [Synonyms]
3-(4'-FLUOROBENZOYL)PROPIONIC ACID
3-(4-FLUOROBENZOYL)PROPIONIC ACID
4-(4-FLUOROPHENYL)-4-OXOBUTANOIC ACID
4-(4-FLUOROPHENYL)-4-OXOBUTYRIC ACID
AKOS BBS-00006441
HALOPERIDOL METABOLITE III
LABOTEST-BB LT00233221
R 11302
4-FLUORO-R-OXO-BENZENEBUTANOIC ACID
Benzenebutanoic acid, 4-fluoro-.gamma.-oxo-
3-(4-Fluorobenzoyl)propionic acid 97%
3-(4-Fluorobenzoyl)propionicacid97%
beta-(4-fluorobenzoyl)propionic acid
4-Fluoro-oxo-benzenebutanoic acid
Haloperidol metabolite III, R 11302
4-Fluoro-γ-oxobenzenebutyric acid
4-Oxo-4-(4-fluorophenyl)butyric acid
β-(p-Fluorobenzoyl)propionic acid | [EINECS(EC#)]
206-679-1 | [Molecular Formula]
C10H9FO3 | [MDL Number]
MFCD00002793 | [Molecular Weight]
196.18 | [MOL File]
366-77-8.mol |
| Chemical Properties | Back Directory | [Appearance]
beige granular powder | [Melting point ]
100-102 °C (lit.) | [Boiling point ]
374.4±22.0 °C(Predicted) | [density ]
1.2441 (estimate) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
powder to crystal | [pka]
4.50±0.17(Predicted) | [color ]
White to Orange to Green | [Water Solubility ]
Insoluble in water. | [BRN ]
958145 | [CAS DataBase Reference]
366-77-8(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,C,Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S22:Do not breathe dust . | [WGK Germany ]
3
| [Hazard Note ]
Corrosive | [HazardClass ]
IRRITANT | [HS Code ]
29183000 |
| Hazard Information | Back Directory | [Chemical Properties]
beige granular powder | [Uses]
7-Fluoro-1-tetralone was prepared from 3-(4-fluorobenzoyl)-propionic acid by Wolff-Kishner reduction followed by ring closure with polyphosphoric acid and other substituted 1-tetralones where commercially available. Reduction of 3-(4-fluorobenzoyl)propionic acid with an excess of tert-butylamine borane (TBAB) in the presence of AlCl3 provided 4-(4-fluorophenyl)-1-butanol (87) in 63% yield for the synthesis of LM-1507 sodium salt. Penfluridol 1-[4,4-bis(4-fluorophenyl)butyl]-4-(4-chloro-3-trifluoromethylphenyl)- 4-hydroxypiperidine, C 28 H 27 ClF 5 NO, M r 523.99, mp 105 - 107°C, is obtained by reducing the ketone of 3-(4-fluorobenzoyl)propionic acid into a lactone. | [Definition]
ChEBI: 4-(4-Fluorophenyl)-4-oxobutanoic acid is an aromatic ketone. | [General Description]
3-(4-Fluorobenzoyl)propionic acid is a metabolite of haloperidol, a dopamine D2 receptor blocker. |
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