| Identification | More | [Name]
Trifluoroacetamide | [CAS]
354-38-1 | [Synonyms]
2,2,2-TRIFLUOROACETAMIDE
TRIFLUOROACETAMIDE
TRIFLUOROACETIC ACID AMIDE
2,2,2-trifluoro-acetamid
CF3CONH2
Triflouroacetamide
TRIFLUOROACETAMIDE 98%
Acetamide, 2,2,2-trifluoro-
2,2,2-TRIFLOUROACETAMIDE
2,2,2-TRIFLOUROACET-AMIDE (TFAA)
Trifluoroacetamide98%
2,2,2-TRIFLOUROACET-AMIDE TFAA 98+%
2,2,2-Trifluoroacetamide (TFAA)
2,2,2-Trifluoroacetamide ,99% | [EINECS(EC#)]
206-559-9 | [Molecular Formula]
C2H2F3NO | [MDL Number]
MFCD00008008 | [Molecular Weight]
113.04 | [MOL File]
354-38-1.mol |
| Chemical Properties | Back Directory | [Appearance]
white to pale yellow or beige crystalline powder | [Melting point ]
65-70 °C (lit.) | [Boiling point ]
162.5 °C (lit.) | [bulk density]
960kg/m3 | [density ]
1.4176 (estimate) | [Fp ]
162-164°C | [storage temp. ]
Store at RT. | [solubility ]
460 g/L (20°C) | [form ]
Crystalline Powder or Crystals | [pka]
12.33±0.50(Predicted) | [color ]
White to pale yellow or beige | [PH]
3.6 (460g/l, H2O, 23℃) | [Water Solubility ]
460 g/L (20 ºC) | [Detection Methods]
GC | [BRN ]
1753625 | [InChIKey]
NRKYWOKHZRQRJR-UHFFFAOYSA-N | [LogP]
0.725 at 23℃ and pH4.83 | [Dissociation constant]
0 at 23℃ | [CAS DataBase Reference]
354-38-1(CAS DataBase Reference) | [NIST Chemistry Reference]
Acetamide, 2,2,2-trifluoro-(354-38-1) | [EPA Substance Registry System]
354-38-1(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [RIDADR ]
1759 | [WGK Germany ]
3
| [Hazard Note ]
Harmful/Irritant | [TSCA ]
T | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29241900 |
| Hazard Information | Back Directory | [Chemical Properties]
white to pale yellow or beige crystalline powder | [Uses]
pharmaceutical intermediate | [Application]
Trifluoroacetamide was used as probe for determination of membrane potential and extra/intracellular volume of erythrocytes by fluorine-19 NMR studies. | [Preparation]
One-pot synthetic approach to produce trifluoroacetamide has been developed using an electrochemical method with the B12 complex as a catalyst under mild conditions, in open air at room temperature. Thirty examples of trifluoroacetamide were synthesized from 1,1,1-trichloro-2,2,2-trifluoroethane (CFC-113a) in moderate to good yields. This user-friendly strategy is compatible with a broad range of trifluoroacetamide syntheses.
10.1142/S1088424621500292 | [General Description]
Trifluoroacetamide is a good quencher of tryptophan fluorescence. |
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