Identification | Back Directory | [Name]
S-ADENOSYL-L-METHIONINE IODIDE SALT | [CAS]
3493-13-8 | [Synonyms]
SAM-I adomet AdoMet, SAM SAM iodide salt SAM-E IODIDE SALT S-adenosylmethione S-ADENOSYLMETHIONINE IODIDE S-ADENOSYL-L-METHIONINE IODIDE S-ADENOSYL METHIONINE IODIDE SALT S-(5'-ADENOSYL)-L-METHIONINE IODIDE S-ADENOSYL-L-METHIONINE IODIDE SALT ADENOSYL-L-METHIONINE, S-IODIDE SALT ADENOSYL-L-METHIONINE IODIDE, S-(RG) S-(5'-deoxy-5'-adenosyl)methionine iodide S-ADENOSYL-L-METHIONINE IODIDE SALT USP/EP/BP S-(5′-Adenosyl)-L-Methionine iodide froM yeast S-(5'-Adenosyl)-L-methionine iodide;SAM iodide salt 5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-Adenosine iodide (3S)-5'-((3-amino-3-carboxypropyl)methylsulphonio)-5'-deoxyadenosine iodide S-(5'-Adenosyl)-L-methionine iodide >=80% (HPLC), >=80% (spectrophotometric assay) (3-amino-4-hydroxy-4-oxobutyl)-[[5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-methylsulfanium iodide [5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl-(3-azanyl-4-hydroxy-4-oxo-butyl)-methyl-sulfanium iodide (5-adenin-9-yl-3,4-dihydroxy-tetrahydrofuran-2-yl)methyl-(3-amino-4-hydroxy-4-keto-butyl)-methyl-sulfonium iodide | [EINECS(EC#)]
222-486-5 | [Molecular Formula]
C15H23IN6O5S | [MDL Number]
MFCD00043192 | [MOL File]
3493-13-8.mol | [Molecular Weight]
526.35 |
Hazard Information | Back Directory | [Uses]
S-(5′-Adenosyl)-L-methionine (SAM, AdoMet) is used as a primary methyl donor molecule in mammalian cell culture and the first step metabolite in methionine biosynthesis. | [Biochem/physiol Actions]
Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury. |
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