| Identification | More | [Name]
L-ETHIONINE | [CAS]
13073-35-3 | [Synonyms]
H-ETH-OH
L-2-AMINO-4-(ETHYLTHIO)BUTYRIC ACID
L-ETHIONINE
2-amino-4-(ethylthio)-butanoicaci
alpha-amino-gamma-(ethylmercapto)butyricacid
homocysteines-ethylether
l-butyricaci
s-ethyl-homocystein
s-ethyl-l-homocystein
S-ethyl-L-homocysteine
L-ETHIONINE 99%
L-ETHIONINE 98+%
(S)-2-Amino-4-(ethylthio)butyric acid
[S,(+)]-2-Amino-4-(ethylthio)butyric acid | [EINECS(EC#)]
235-966-4 | [Molecular Formula]
C6H13NO2S | [MDL Number]
MFCD00002626 | [Molecular Weight]
163.24 | [MOL File]
13073-35-3.mol |
| Chemical Properties | Back Directory | [Appearance]
White Solid | [Melting point ]
280 °C (dec.)(lit.) | [alpha ]
D24 +25.1°; D23 +20.1° (1N HCl) (Armstrong, Lewis) | [density ]
1.085 (estimate) | [refractive index ]
22 ° (C=1, 1mol/L HCl) | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [solubility ]
Aqueous Acid (Slightly), Water (Slightly) | [Boiling point ]
310.4±37.0 °C(Predicted) | [form ]
solid | [pka]
2.23±0.10(Predicted) | [color ]
White to Off-White | [Merck ]
3738 | [CAS DataBase Reference]
13073-35-3(CAS DataBase Reference) | [EPA Substance Registry System]
L-Ethionine (13073-35-3) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [RTECS ]
ES6825300
| [HS Code ]
2930.90.4950 | [Hazardous Substances Data]
13073-35-3(Hazardous Substances Data) | [Toxicity]
rat,LD,intraperitoneal,> 1gm/kg (1000mg/kg),LIVER: OTHER CHANGESLIVER: CHANGES IN LIVER WEIGHT,Acta Pathologica Japonica. Vol. 39, Pg. 281, 1989. |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
Ethionine-induced inhibition of protein synthesis and lowering of ATP level in the liver. | [Definition]
ChEBI: An S-ethylhomocysteine that has S-configuration at the chiral centre. | [Purification Methods]
Likely impurities are N-acetyl-(R and S)-ethionine, S-methionine, and R-ethionine. Crystallise it from water by adding 4volumes of EtOH or 85% aqueous EtOH. It sublimes at 196-216o/0.3mm with 99.1% recovery and unracemised [Gross & Gradsky J Am Chem Soc 77 1678 1955]. [Weiss & Stekol J Am Chem Soc 73 2399 1951, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2658, 2659 1961, Beilstein 4 IV 3194.] |
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