| Identification | More | [Name]
2,2,6,6-Tetramethyl-4-piperidone hydrochloride | [CAS]
33973-59-0 | [Synonyms]
2,2,6,6-TETRAMETHYL-4-AZACYCLOHEXANONE HYDROCHLORIDE
2,2,6,6-TETRAMETHYL-4-PIPERIDONE HYDROCHLORIDE
2,2,6,6-TETRAMETHYLPIPERIDONE-4 HYDROCHLORIDE
TEMPIDONE
TIMTEC-BB SBB003626
TMP=O
TRIACETONAMINE
TRIACETONAMINE HYDROCHLORIDE
TRIACETONEAMINE HYDROCHLORIDE
VINCUBINE
2,2,6,6-tetramethyl-4-piperidinonhydrochloride
2,2,6,6-tetramethylpiperidin-4-one hydrochloride
2,2,6,6-Tetramethyl-4-piperidoneHCl
2,2,6,6-Tetramethylpiperidin-4-one hydrochloride 97%
2,2,6,6-TETRAMETHYL-4-PIPERIDONE HYDROCHLORIDE 97%
4-Piperidinone, 2,2,6,6-tetramethyl-, hydrochloride
2,2,6,6-Tetramethyl-4-piperidinone·hydrochloride | [EINECS(EC#)]
251-769-6 | [Molecular Formula]
C9H18ClNO | [MDL Number]
MFCD00012768 | [Molecular Weight]
191.7 | [MOL File]
33973-59-0.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [F ]
8 | [Hazard Note ]
Irritant | [HS Code ]
2933399990 |
| Hazard Information | Back Directory | [Chemical Properties]
white to slightly beige crystalline powder | [Uses]
2,2,6,6-Tetramethyl-4-piperidone hydrochloride has been used as a reagent injected in the micromixer using a Rheodyne injection valve for introducing discrete sample pulses into the miniaturised-SYNthesis and Total Analysis System (πSYNTAS). | [in vivo]
Triacetonamine (Purchased from MCE; 200 mg, 300 mg, 400 mg/Kg/day; gavage; 2 days) hydrochloride shows typical hepatoenteropathology of ALF with 300 mg/Kg/day and 400 mg/Kg/day, while the group of 400 mg/Kg/day had higher mortality[2]. | Animal Model: | Rats (half male and female, 6-8 weeks old, 200?±?10 g)[2] | | Dosage: | 200 mg, 300 mg, 400 mg/Kg | | Administration: | Gavage; daily; 2 days | | Result: | Showed typical hepatoenteropathology of ALF with 300 mg/Kg/day and 400 mg/Kg/day, while the group of 400 mg/Kg/day had higher mortality.
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| [Purification Methods]
Purify the salt by recrystallisation from EtOH/Et2O, MeCN or Me2CO/MeOH. The free base has m 37-39o (after sublimation), b 102-105o/18mm, and the hydrate has m 56-58o (wet Et2O); the hydrobromide has m 203o (from EtOH/Et2O), and the picrate has m 196o (from aqueous EtOH). [Sandris & Ourisson Bull Soc Chim Fr 345 1958, Beilstein 21 H 246, 21 I 273, 21 II 222, 21 III/IV 3278, 21/6 V 538.] |
| Spectrum Detail | Back Directory | [Spectrum Detail]
2,2,6,6-Tetramethyl-4-piperidone hydrochloride(33973-59-0)MS
2,2,6,6-Tetramethyl-4-piperidone hydrochloride(33973-59-0)1HNMR
2,2,6,6-Tetramethyl-4-piperidone hydrochloride(33973-59-0)13CNMR
2,2,6,6-Tetramethyl-4-piperidone hydrochloride(33973-59-0)IR1
2,2,6,6-Tetramethyl-4-piperidone hydrochloride(33973-59-0)IR2
2,2,6,6-Tetramethyl-4-piperidone hydrochloride(33973-59-0)Raman
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