Identification | More | [Name]
H-ALA-PHE-OH | [CAS]
3061-90-3 | [Synonyms]
ALA-PHE L-ALA-PHE NSC 89630 Ala-Phe-OH L-Ala-L-phe H-ALA-PHE-OH L-Ala-L-Phe-OH alanylphenylalanine L-alanyl-phenylalanine Ala-Phe-OH≥ 98% (HPLC) L-ALANYL-L-PHENYLALANINE L-Phenylalanine, L-alanyl- N-L-Alanyl-L-phenylalanine (S)-2-((S)-2-AMinopropanaMido)-3-phenylpropanoic acid (2S)-2-[(2S)-2-aminopropanamido]-3-phenylpropanoic acid (S)-2-[[(S)-2-Aminopropionyl]amino]-3-phenylpropionic acid (2S)-2-[[(2S)-2-aminopropanoyl]amino]-3-phenylpropanoic acid | [Molecular Formula]
C12H16N2O3 | [MDL Number]
MFCD00066031 | [Molecular Weight]
236.27 | [MOL File]
3061-90-3.mol |
Hazard Information | Back Directory | [Chemical Properties]
White to off-white powder | [Uses]
Alanylphenylalanine is a potential antitumor agent that targets DNA via metal coordination. The complex of Alanylphenylalanine and Au (III) can bind to DNA and inhibit tumor cell proliferation[1][2]. | [Definition]
ChEBI: A dipeptide formed from L-alanyl and L-phenylalanine residues. | [Biological Activity]
Alanyl dipeptides such as ala-leuala-lysala-glyala-proala-tyr and ala-phe may be used in physicochemical studies or to evaluate dipeptide separation technologies. Alanyl dipeptides may also be used for studying cell uptake mechanismsdipeptide metabolism or cell growth supplementation benefits. | [storage]
Store at -20°C | [References]
[1] Zhang ZH, et al. An integrated lipidomics and metabolomics reveal nephroprotective effect and biochemical mechanism of Rheum officinale in chronic renal failure. Sci Rep. 2016 Feb 23;6:22151. DOI:10.1038/srep22151 [2] Koleva B B, et al. The dipeptide alanylphenylalanine (H-Ala-Phe-OH)-protonation and coordination ability with Au (III)[J]. Journal of Molecular Structure, 2007, 831(1-3): 165-173. |
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