| Identification | More | [Name]
Octyl-beta-D-glucopyranoside | [CAS]
29836-26-8 | [Synonyms]
1-O-N-OCTYL-BETA-D-GLUCOPYRANOSIDE
1-O-OCTYL-BETA-D-GLUCOPYRANOSIDE
CHAPSO
N-OCTYL-B-D-GLUCOSIDE
N-OCTYL-BETA-D-GLC
N-OCTYL-BETA-D-GLUCOPYRANOSIDE
N-OCTYL-BETA-D-GLUCOSIDE
N-OCTYL GLUCOSIDE
OCTYL B-D-GLUCOPYRANOSIDE
OCTYL-B-D-GLUCOPYRANOSIDE, N-
OCTYL BETA-D-GLUCOPYRANOSIDE
OCTYL BETA-GLUCOSIDE
OCTYL B-GLUCOSIDE
OCTYL GLUCOSIDE
OG
OGD
OGP
octyl-beta-d-glucoside
CAPRYLYL GLUCOSIDE
N-OCTYL-B-D-GLUCOPYRANOSIDE | [EINECS(EC#)]
249-887-8 | [Molecular Formula]
C14H28O6 | [MDL Number]
MFCD00063288 | [Molecular Weight]
292.37 | [MOL File]
29836-26-8.mol |
| Chemical Properties | Back Directory | [Appearance]
white crystalline powder and chunks | [Melting point ]
105 °C
| [alpha ]
-32 º (c=5, water) | [Boiling point ]
354.3°C (rough estimate) | [density ]
1.0869 (rough estimate) | [refractive index ]
-27 ° (C=1, MeOH) | [storage temp. ]
2-8°C
| [solubility ]
DMSO (Slightly), Water (Slightly) | [form ]
Crystalline Powder and Chunks | [pka]
12.95±0.70(Predicted) | [color ]
White | [Water Solubility ]
3 g/10 mL | [Sensitive ]
Hygroscopic | [Merck ]
6767 | [BRN ]
84118 | [Stability:]
Hygroscopic | [InChIKey]
HEGSGKPQLMEBJL-QNOVJUQQSA-N | [LogP]
0.887 (est) | [CAS DataBase Reference]
29836-26-8(CAS DataBase Reference) | [EPA Substance Registry System]
29836-26-8(EPA Substance) |
| Safety Data | Back Directory | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [HS Code ]
29400090 |
| Hazard Information | Back Directory | [Description]
n-Octyl-β-D-glucopyranoside is a non–ionic detergent intended for solubilizing membrane–bound proteins in their native state and for the preparation of lipid vesicles. n-Octyl-β-D-glucopyranoside has a well–defined chemical structure, small uniform micelles, and high water solubility, which make n-Octyl-β-D-glucopyranoside superior to most other nonionic detergents for membrane solubilization. Because of the high critical micelle concentration (20-25 mM), n-Octyl-β-D-glucopyranoside has the additional advantage of being removed easily by dialysis when compared to bile salts. n-Octyl-β-D-glucopyranoside is also known as N-Octyl glucoside, OGP, OG, n-Octylglucoside, and octyl-β-D-glucopyranoside.
| [Chemical Properties]
white crystalline powder and chunks | [Uses]
A nonionic detergent for the solubilization of membrane bound protein. | [Uses]
Detergent and surfactant for biological systems. | [Uses]
Unlike many other detergents, octyl glucoside is a pure, single compound of defined structure. Very effective for insulin binding and solubilization studies of membran | [Definition]
ChEBI: Octyl beta-D-glucopyranoside is an beta-D-glucoside in which the anomeric hydrogen of beta-D-glucopyranose is substituted by an octyl group. It has a role as a plant metabolite. | [Purification Methods]
Purify octyl--D-glucopyranoside by recrystallisation from Me2CO. It is hygroscopic and should be stored in a well-stoppered container. [Noller & Rockwell J Am Chem Soc 6 0 2076 1938, Pigman & Richtmyer J Am Chem Soc 64 369 1942.] It is a UV transparent non-ionic dialysable detergent for solubilising membrane proteins. The D-isomer with [] D 20 +118o (c 1, MeOH) has similar solubilising properties. [Lazo & Quinn Anal Biochem 102 68 1980, Stubbs et al. Biochim Biophys Acta 426 46 1976, Beilstein 17/7 V 38.] |
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