| Identification | More | [Name]
Oxazole | [CAS]
288-42-6 | [Synonyms]
1,3-OXAZOLE
OXAZOLE
RARECHEM AM LA 0030
Oxazole,98+%
Oxazol | [EINECS(EC#)]
206-020-8 | [Molecular Formula]
C3H3NO | [MDL Number]
MFCD00009751 | [Molecular Weight]
69.06 | [MOL File]
288-42-6.mol |
| Chemical Properties | Back Directory | [Appearance]
Colorlesstolightyellowliqui | [Melting point ]
−87-−84 °C(lit.)
| [Boiling point ]
69-70 °C(lit.)
| [density ]
1.05 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.425(lit.)
| [Fp ]
66 °F
| [storage temp. ]
Refrigerator | [solubility ]
Chloroform, Methanol (Slightly) | [form ]
clear liquid | [pka]
0.8(at 33℃) | [color ]
Colorless to Almost colorless | [Water Solubility ]
Miscible with alcohol and ether. Slightly miscible with water. | [BRN ]
103851 | [LogP]
0.120 | [CAS DataBase Reference]
288-42-6(CAS DataBase Reference) | [NIST Chemistry Reference]
Oxazole(288-42-6) |
| Safety Data | Back Directory | [Hazard Codes ]
F,Xi | [Risk Statements ]
R11:Highly Flammable.
R41:Risk of serious damage to eyes.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
UN 1993 3/PG 1
| [WGK Germany ]
3
| [HazardClass ]
3 | [PackingGroup ]
II | [HS Code ]
29349990 |
| Questions And Answer | Back Directory | [Description]
Oxazole is the primary compound for a various class of heterocyclic aromatic organic compounds, which include azoles with a nitrogen and an oxygen separated by one carbon. Oxazole is a weak base and an aromatic compound.
| [Preparation]
There are various methods of synthesizing oxazole in organic chemistry including Van Leusen reaction with TosMIC and aldehydes, Robinson-Gabriel preparation by dehydration of 2-acylaminoketones, and Bredereck reaction with formamide. Oxazole result from the oxidation and cyclization of threonine and serine non-ribosomal peptides.
|
| Hazard Information | Back Directory | [Chemical Properties]
Colorlesstolightyellowliqui | [Uses]
Oxazole and its derivatives are actively involved as building blocks for bio chemicals and pharmaceuticals like flopristin and darglitazone. It is also involved in industrial applications such as in dyes, fluorescent brightening agents, textile auxiliaries and plastics. | [Definition]
ChEBI: A five-membered monocyclic heteroarene that is an analogue of cyclopentadiene with O in place of CH2 at position 1 and N in place of CH at position 3. | [Definition]
oxazole: A heterocyclic compoundhaving a nitrogen atom and an oxygenatom in a five-membered ring,C3H3NO. | [General Description]
Oxazole ring is present in various natural products. The diradical interactions in the ring-opening reaction of oxazole were studied. |
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